Detailed information of TA system TA155390

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 807317..807958
• Replicon: chromosome
• Accession: NZ_CP051869
• Organism: Acinetobacter baumannii strain Ab-D10a-a

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: A0A858S2K0
• Locus tag: HIN87_RS03930
• Protein ID: WP_031999513.1
• Coordinates: 807317..807706 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: HIN87_RS03935
• Protein ID: WP_011860336.1
• Coordinates: 807713..807958 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HIN87_RS03915	802435..804630	-	2196	WP_001158905.1	TRAP transporter large permease subunit	-
HIN87_RS03920	804818..805384	-	567	WP_000651536.1	rhombosortase	-
HIN87_RS03925	805462..806547	-	1086	WP_031999514.1	hypothetical protein	-
HIN87_RS03930	807317..807706	-	390	WP_031999513.1	membrane protein	Toxin
HIN87_RS03935	807713..807958	-	246	WP_011860336.1	succinate dehydrogenase assembly factor 2	Antitoxin
HIN87_RS03940	808158..809330	+	1173	WP_017725189.1	acyl-CoA dehydrogenase family protein	-
HIN87_RS03945	809379..810869	-	1491	WP_000415132.1	NAD(P)/FAD-dependent oxidoreductase	-
HIN87_RS03950	811051..811428	-	378	WP_001216380.1	50S ribosomal protein L17	-
HIN87_RS03955	811447..812454	-	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (6-78)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15598.85 Da
• Isoelectric Point: 10.3889

>T155390 WP_031999513.1 NZ_CP051869:c807706-807317 [Acinetobacter baumannii]
MVNHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYQSQNTV
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T155390 NZ_CP068800:c2803144-2802968 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATGGCAGCAACCATTTAAAACTCAG
GTTTCACGGGAGGCGCAGTGTCATGCCGCGTCACCCCAGCGAAGAGATTAAAGAACCATTGCGTAAAGCCATTCTGAAAC
AACTCGGTTTGAGTTAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9842.27 Da
• Isoelectric Point: 4.9001

>AT155390 WP_011860336.1 NZ_CP051869:c807958-807713 [Acinetobacter baumannii]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLKHYVH
G

Nucleotide

• Length: 246 bp

>AT155390 NZ_CP068800:c2802922-2802506 [Escherichia coli]
ATGCGTTATCCCGTCACTCTTACACCCGCGCCGGAAGGCGGTTATATGGTTTCTTTTGTGGATATCCCTGAAGCGTTGAC
CCAGGGCGAAACTGTCGCTGAAGCGATGGAAGCGGCAAAAGATGCTTTACTGACCGCATTTGATTTTTATTTTGAAGATA
ACGAGCTTATCCCTTTACCTTCGCCATCAAATAGTCACGATCACTTTATTGAAGTGCCTTTGAGCGTCGCCTCTAAAGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGGCGAATTGGCAAACCTAAACAGGAAAT
TACTCGCTTATTTAACTTGCACCATGCGACAAAAATCGACGCCGTCCAGCTTGCGGCTAAGGCGCTTGGCAAAGAGTTAT
CGCTGGTGATGGTTTAA

Structures

Toxin

• AlphaFold DB: A0A858S2K0