Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3264284..3264925 Replicon chromosome
Accession NZ_CP051862
Organism Acinetobacter baumannii strain Ab-C102

Toxin (Protein)


Gene name cptA Uniprot ID A0A829RKD8
Locus tag HIN89_RS15455 Protein ID WP_002125600.1
Coordinates 3264284..3264673 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag HIN89_RS15460 Protein ID WP_011860336.1
Coordinates 3264680..3264925 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HIN89_RS15440 3259402..3261597 - 2196 WP_001158905.1 TRAP transporter large permease subunit -
HIN89_RS15445 3261785..3262351 - 567 WP_000651536.1 rhombosortase -
HIN89_RS15450 3262429..3263514 - 1086 WP_000049106.1 hypothetical protein -
HIN89_RS15455 3264284..3264673 - 390 WP_002125600.1 hypothetical protein Toxin
HIN89_RS15460 3264680..3264925 - 246 WP_011860336.1 succinate dehydrogenase assembly factor 2 Antitoxin
HIN89_RS15465 3265125..3266297 + 1173 WP_002125555.1 acyl-CoA dehydrogenase family protein -
HIN89_RS15470 3266346..3267500 - 1155 WP_004738527.1 IS4 family transposase -
HIN89_RS15475 3267628..3269118 - 1491 WP_002125480.1 NAD(P)/FAD-dependent oxidoreductase -
HIN89_RS15480 3269300..3269677 - 378 WP_001216380.1 50S ribosomal protein L17 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 3266346..3267500 1154


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15662.98 Da        Isoelectric Point: 10.4623

>T155379 WP_002125600.1 NZ_CP051862:c3264673-3264284 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKIWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKKLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

>T155379 NZ_CP068800:217181-217288 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTCTGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9842.27 Da        Isoelectric Point: 4.9001

>AT155379 WP_011860336.1 NZ_CP051862:c3264925-3264680 [Acinetobacter baumannii]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLKHYVH
G

Download         Length: 246 bp

>AT155379 NZ_CP068800:c217132-217069 [Escherichia coli]
GTCTAGATGCAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A829RKD8

Antitoxin

Source ID Structure

References