Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 2171164..2172047 Replicon chromosome
Accession NZ_CP051857
Organism Pseudomonas sp. SK

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag HG549_RS09970 Protein ID WP_170029330.1
Coordinates 2171610..2172047 (+) Length 146 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag HG549_RS09965 Protein ID WP_170029329.1
Coordinates 2171164..2171613 (+) Length 150 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HG549_RS09940 2166588..2167787 + 1200 WP_170029324.1 sugar transporter -
HG549_RS09945 2167839..2168423 - 585 WP_170029325.1 LysE family transporter -
HG549_RS09950 2168474..2169304 - 831 WP_170029326.1 AraC family transcriptional regulator -
HG549_RS09955 2169354..2170277 - 924 WP_170029327.1 LysR family transcriptional regulator -
HG549_RS09960 2170382..2171035 + 654 WP_170029328.1 oxygen-insensitive NAD(P)H nitroreductase -
HG549_RS09965 2171164..2171613 + 450 WP_170029329.1 DUF2384 domain-containing protein Antitoxin
HG549_RS09970 2171610..2172047 + 438 WP_170029330.1 RES family NAD+ phosphorylase Toxin
HG549_RS09975 2172055..2173209 - 1155 WP_170029331.1 aminotransferase class V-fold PLP-dependent enzyme -
HG549_RS09980 2173404..2174330 - 927 WP_170029332.1 LysR family transcriptional regulator -
HG549_RS09985 2174470..2175693 + 1224 WP_170029333.1 acyl-CoA dehydrogenase -
HG549_RS09990 2175690..2176499 - 810 WP_170034130.1 OBAP family protein -
HG549_RS09995 2176655..2177023 + 369 WP_170029334.1 DNA binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-137)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(33-91)


Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 16019.29 Da        Isoelectric Point: 6.0718

>T155358 WP_170029330.1 NZ_CP051857:2171610-2172047 [Pseudomonas sp. SK]
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPAGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQ
PGWSTQTELTRGLGNRFLDDCSALLLPVPSAIMPRTTNYLFNPRHPQAHSAKLDVEDFTPDSRLF

Download         Length: 438 bp

>T155358 NZ_CP068799:1984731-1984982 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Antitoxin


Download         Length: 150 a.a.        Molecular weight: 16990.56 Da        Isoelectric Point: 6.3398

>AT155358 WP_170029329.1 NZ_CP051857:2171164-2171613 [Pseudomonas sp. SK]
MLAEVLRDNGYHEYRARLHALLEIPELASDFEIHTRITHGFAATWLVKLTELGVFTPVERDQIIPLRTLKSRIERDQPLT
VEESDRLFRSAHITAMAEAVFGDAAKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGFGL

Download         Length: 450 bp

>AT155358 NZ_CP068799:1984979-1985233 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAAATTATCAAAGATACACGCAGAACACCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GCTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References