Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelE-RHH
Location 1773..2320 Replicon plasmid pSCU-111-1
Accession NZ_CP051728
Organism Escherichia coli strain SCU-111

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag HHJ28_RS22810 Protein ID WP_169062069.1
Coordinates 2039..2320 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag HHJ28_RS22805 Protein ID WP_048889353.1
Coordinates 1773..2042 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HHJ28_RS22800 1..858 + 858 WP_169062068.1 incFII family plasmid replication initiator RepA -
HHJ28_RS22805 1773..2042 + 270 WP_048889353.1 hypothetical protein Antitoxin
HHJ28_RS22810 2039..2320 + 282 WP_169062069.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HHJ28_RS22815 2366..3208 + 843 Protein_4 3'-5' exonuclease -
HHJ28_RS22820 3169..3627 + 459 WP_169062137.1 hypothetical protein -
HHJ28_RS22825 4331..5104 - 774 WP_169062070.1 tannase/feruloyl esterase family alpha/beta hydrolase -
HHJ28_RS22830 5270..5815 - 546 WP_169062138.1 isopentenyl-diphosphate Delta-isomerase -
HHJ28_RS22835 5909..6625 - 717 WP_087888581.1 DUF554 domain-containing protein -
HHJ28_RS22840 6643..7212 - 570 WP_087888585.1 UbiX family flavin prenyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - acrB / pet / etpB / etpB / cdtC / cdtB / cdtA / etpA / etpB 1..189717 189717


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10901.62 Da        Isoelectric Point: 8.4615

>T155106 WP_169062069.1 NZ_CP051728:2039-2320 [Escherichia coli]
MMEIFWTMLASQDRKRIREYIAEQNLIAAIELDERIGYSASSLAGQPYKGRNGRVEGTRELVIHPHFVLVYEVDIQWGKV
YILRVLHTAQKWP

Download         Length: 282 bp

>T155106 NZ_CP068647:1899226-1899504 [Vibrio parahaemolyticus]
ATGATTTTATGGGAAGAAGAGTCACTTAATGATCGTGAAAAGATCTTTGAGTTTCTCTATGACTTCAACCCTGATGCGGC
AGAGAAAACTGACAACCTCATTGAAGCAAAAGTGGAGAACTTGCTAGAGCAGCCACTAATGGGTGTGCAGCGAGATGGTA
TTCGTGGGCGATTACTTATAATCCCTGATATTTCAATGATCGTCTCCTATTGGATCGAAGGCGACATTATCCGAATCATG
CGCGTGCTTCACCAGAAACAAAAATTTCCTATGGATTGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10252.58 Da        Isoelectric Point: 7.2057

>AT155106 WP_048889353.1 NZ_CP051728:1773-2042 [Escherichia coli]
MAQVNMSLRIDAELKDAFMAAAKSMDRNGSQLIRDFMRQTVERQHNTWFRDQVAEGRQQLERGDVLPHDMVESSAAAWRD
EMSRKVAGK

Download         Length: 270 bp

>AT155106 NZ_CP068647:1898945-1899229 [Vibrio parahaemolyticus]
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACAAAACGCCTAGCTCAACAAATGGCTGAGAGCCAAGGTCGCAC
TCTAAGTGACGCATGCCGTGAACTTACTGAGCAACTCGCTGAGCAACAAAGAAAAACATTATCTCACGATGCATGGCTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGTTTGACTCAGGAAAATCCGTTTTCGTTGACCACCAAACTGCTAAATCTCGA
ATGGAAGAGCGCAAAGCCAGAATCCGTAATCGAGGTAAGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References