Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/Txe-YefM
Location 1968301..1968803 Replicon chromosome
Accession NZ_CP051684
Organism Duganella sp. AF9R3

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag HH213_RS09160 Protein ID WP_169112059.1
Coordinates 1968540..1968803 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HH213_RS09155 Protein ID WP_169112058.1
Coordinates 1968301..1968543 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HH213_RS09135 1964000..1965211 - 1212 WP_110845569.1 MFS transporter -
HH213_RS09140 1965283..1966278 - 996 WP_169112055.1 Gfo/Idh/MocA family oxidoreductase -
HH213_RS09145 1966327..1967124 - 798 WP_169112056.1 DUF3025 domain-containing protein -
HH213_RS09150 1967128..1968180 - 1053 WP_169112057.1 dihydroorotase -
HH213_RS09155 1968301..1968543 + 243 WP_169112058.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
HH213_RS09160 1968540..1968803 + 264 WP_169112059.1 Txe/YoeB family addiction module toxin Toxin
HH213_RS09165 1968800..1969135 - 336 WP_169112060.1 DUF2314 domain-containing protein -
HH213_RS09170 1970147..1971595 - 1449 WP_169112061.1 amidohydrolase family protein -
HH213_RS09175 1971595..1972320 - 726 WP_169112062.1 amino acid ABC transporter ATP-binding protein -
HH213_RS09180 1972530..1973786 + 1257 WP_110845578.1 dicarboxylate/amino acid:cation symporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1962953..1974026 11073


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-68)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10184.84 Da        Isoelectric Point: 10.2660

>T154745 WP_169112059.1 NZ_CP051684:1968540-1968803 [Duganella sp. AF9R3]
VSWQLVYSRQAEKDAKKLAVAHLKKQTQALLDVLASDPFARPPPFEKLVGDLAGTYSRRINIHHRLVYEVFPDQKIVRIL
RMWTHYD

Download         Length: 264 bp

>T154745 NZ_CP068247:1297836-1297931 [Staphylococcus sp. T93]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8673.78 Da        Isoelectric Point: 4.7144

>AT154745 WP_169112058.1 NZ_CP051684:1968301-1968543 [Duganella sp. AF9R3]
MDTISASEARARLYTLIDEAAASHAPVTITGKRNNAVLVSAEDWAAIQETLHLLSVPGMRESILAARAEPLENNSKELSW

Download         Length: 243 bp

>AT154745 NZ_CP068247:c1298018-1297959 [Staphylococcus sp. T93]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References