Detailed information of TA system TA154744

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pasABC/RelE-HTH
• Location: 1100974..1101460
• Replicon: chromosome
• Accession: NZ_CP051684
• Organism: Duganella sp. AF9R3

Toxin (Protein)

• Gene name: pasB
• Uniprot ID: -
• Locus tag: HH213_RS05195
• Protein ID: WP_169111193.1
• Coordinates: 1101185..1101460 (+)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: pasA
• Uniprot ID: -
• Locus tag: HH213_RS05190
• Protein ID: WP_169111191.1
• Coordinates: 1100974..1101201 (+)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HH213_RS05180	1097537..1099174	-	1638	WP_169111189.1	alpha glucosidase	-
HH213_RS05185	1099394..1100956	+	1563	WP_169114970.1	oligopeptide:H+ symporter	-
HH213_RS05190	1100974..1101201	+	228	WP_169111191.1	CopG family transcriptional regulator	Antitoxin
HH213_RS05195	1101185..1101460	+	276	WP_169111193.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HH213_RS05200	1101568..1104279	+	2712	WP_169111195.1	DUF3372 domain-containing protein	-
HH213_RS05205	1104283..1104630	+	348	WP_169111197.1	PKD domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-88)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10568.28 Da
• Isoelectric Point: 10.2111

>T154744 WP_169111193.1 NZ_CP051684:1101185-1101460 [Duganella sp. AF9R3]
MAWQIDYTRQAQRQLLKLDKAAARRILDYMDQQVAPQADPRSLGKALTGAKLGSYWRYRVGDYRIICDIQDGILHVLVVG
IGYRKQIYRQV

Nucleotide

• Length: 276 bp

>T154744 NZ_CP068247:c314459-314271 [Staphylococcus sp. T93]
ATGTCTTTACATTTTGCAATTCTGTTTTGGCTAGCATTAATTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAATGAA
AAAAACTAGCAAAGAATCTAAAAAAGAGTCCTATTTAAGTTTCACTGTCATTCTCTATATTTTTGGATTCGCTATATTAA
TATACACATTTATATTTGGTGTGCTATAA

Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 8452.57 Da
• Isoelectric Point: 4.5859

>AT154744 WP_169111191.1 NZ_CP051684:1100974-1101201 [Duganella sp. AF9R3]
MAISFELDDKTEQRLRKLAMRTGKSLDAHLQELIAQSIDDLEDLYLAEATMQRVASGKEPVYSSEQVRKNLGLAD

Nucleotide

• Length: 228 bp

>AT154744 NZ_CP068247:c314748-314488 [Staphylococcus sp. T93]
ATGAATAACATTTTGTTAAATGCTATCAATATAGTTATTACTACCACTTTTGTTATCTTTAATATTTTAATCACATATAA
TAAAGATTTAGATGATTTATGTTGGCTCCTGCCTGGTATTATCATTTGTGGTGTGATACTCATCGTATCCTTTACCATTG
CAATGATAACTAAAAACTGGTTAAGTGAAATATTATTTTTTATAAATATCGTACTCGTTCTCTATTACATTTATCCTATT
TTTTATAGTTTTATAGGTTAA