Detailed information of TA system TA154740

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 2205003..2205525
• Replicon: chromosome
• Accession: NZ_CP051666
• Organism: Marinobacterium sp. LSUCC0821

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HH196_RS10740
• Protein ID: WP_169452112.1
• Coordinates: 2205241..2205525 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: HH196_RS10735
• Protein ID: WP_169452111.1
• Coordinates: 2205003..2205251 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HH196_RS10705	2201096..2201362	+	267	WP_169452105.1	ribbon-helix-helix protein, CopG family	-
HH196_RS10710	2201365..2201643	+	279	WP_169452106.1	type II toxin-antitoxin system RelE/ParE family toxin	-
HH196_RS10715	2202084..2203238	+	1155	WP_169452107.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
HH196_RS10720	2203238..2203714	+	477	WP_169452108.1	cyclic pyranopterin monophosphate synthase MoaC	-
HH196_RS10725	2203720..2203974	+	255	WP_169452109.1	molybdopterin converting factor subunit 1	-
HH196_RS10730	2203985..2204701	+	717	WP_169452110.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
HH196_RS10735	2205003..2205251	+	249	WP_169452111.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
HH196_RS10740	2205241..2205525	+	285	WP_169452112.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HH196_RS10745	2205808..2206038	+	231	WP_169452113.1	antitoxin	-
HH196_RS10750	2206038..2206436	+	399	WP_169452114.1	tRNA(fMet)-specific endonuclease VapC	-
HH196_RS10755	2206760..2207239	+	480	WP_169452115.1	transcription/translation regulatory transformer protein RfaH	-
HH196_RS10760	2207232..2208179	-	948	WP_169452116.1	tyrosine-type recombinase/integrase	-
HH196_RS10765	2208324..2208752	+	429	WP_169452117.1	helix-turn-helix domain-containing protein	-
HH196_RS10770	2208749..2209480	+	732	WP_169452118.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	-
HH196_RS10775	2209528..2209608	+	81	WP_169452391.1	hypothetical protein	-
HH196_RS10780	2209845..2210177	+	333	WP_169452119.1	MarR family EPS-associated transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (7-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 11043.09 Da
• Isoelectric Point: 10.9525

>T154740 WP_169452112.1 NZ_CP051666:2205241-2205525 [Marinobacterium sp. LSUCC0821]
MSYKLAFRQDAKKEWDALSPSVKEQFKKKLVERLENPRIPSSKLSGVKDRYKIKLRQAGFRLVYEVRDEIVTVVVVAVGK
RERNAVYKMAMKRI

Nucleotide

• Length: 285 bp

>T154740 NZ_CP068241:913664-913870 [Staphylococcus sp. 11-B-312]
ATGGAATCACAAACGATTTATTTACGTAAAATAGATAATAAACAAGATAAGCTTCAAATAGAAAGAACATTATCACAAAT
CATCGGTGTGAATCATGTTTCAGTTGAAATTGAAAAAGCACAAGTGTTTATAGAATTTGAAACACCAGCAAGTTTAAACA
ATTTAGAAAAAGACTTATATGATTTAGGATTTGAAATTTTGTATTAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9194.47 Da
• Isoelectric Point: 3.8189

>AT154740 WP_169452111.1 NZ_CP051666:2205003-2205251 [Marinobacterium sp. LSUCC0821]
MPRQVLADLCVSISELKKNPSVVVAQGDGFPVAVLNRNEPDFYCIPAAAWEEITDRLEDIELNMIADQRVDQPIIEVDIN
EL

Nucleotide

• Length: 249 bp

>AT154740 NZ_CP068241:913356-913649 [Staphylococcus sp. 11-B-312]
ATGGCAGAAATGCAAAAAGCGCATCATTCTGAACAAATTAAATCAAATTTAAAATCTCGTTTAAATCGCATTGAAGGACA
AGTAAGAGCGATCAATCGTATGATTGATGAAGATGTATATTGTGATGATGTGCTTACACAAATTAGAGCGACAAGATCAG
CACTTAATAGTGTTGCTACGAAATTATTAGATCACCATATGAAAAGTTGTATTATGGATAAAGTGAACCAAGGTGAGCAA
CAAGAAGCAATGGATGAGTTGTTGGTAACTTTCCAAAAGTTAATGAAAGATTAG