Detailed information of TA system TA154607

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ccdAB/CcdA(antitoxin)
• Location: 3032116..3032669
• Replicon: chromosome
• Accession: NZ_CP051652
• Organism: Pectobacterium carotovorum strain WPP14

Toxin (Protein)

• Gene name: ccdB
• Uniprot ID: -
• Locus tag: HER17_RS13710
• Protein ID: WP_010305012.1
• Coordinates: 3032116..3032430 (-)
• Length: 105 a.a.

Antitoxin (Protein)

• Gene name: ccdA
• Uniprot ID: -
• Locus tag: HER17_RS13715
• Protein ID: WP_010305008.1
• Coordinates: 3032433..3032669 (-)
• Length: 79 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HER17_RS13685	3027173..3028168	+	996	WP_010305031.1	aldo/keto reductase	-
HER17_RS13690	3028278..3028955	-	678	WP_010305027.1	NAD(P)H-dependent oxidoreductase	-
HER17_RS13695	3029188..3029781	-	594	WP_010305023.1	NAD(P)H-dependent oxidoreductase	-
HER17_RS13700	3030000..3030902	+	903	WP_010305019.1	AraC family transcriptional regulator	-
HER17_RS13705	3031616..3031903	+	288	WP_010305018.1	hypothetical protein	-
HER17_RS13710	3032116..3032430	-	315	WP_010305012.1	CcdB family protein	Toxin
HER17_RS13715	3032433..3032669	-	237	WP_010305008.1	type II toxin-antitoxin system CcdA family antitoxin	Antitoxin
HER17_RS13720	3032812..3033261	-	450	Protein_2684	ArdC family protein	-
HER17_RS13725	3033624..3034517	+	894	Protein_2685	IS3 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	3033624..3033791	167

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin CcdB (2-103)

Antitoxin

• Post-segregation antitoxin CcdA (9-78)

Sequences

Toxin

Protein

• Length: 105 a.a.
• Molecular weight: 11521.45 Da
• Isoelectric Point: 7.9859

>T154607 WP_010305012.1 NZ_CP051652:c3032430-3032116 [Pectobacterium carotovorum]
MQFTVYGNTGKSVVYPLLLDVTSDIIGQLNRRIVIPLLPIEKYPAGRRPDRLVPVVRLTDGKEYAVMTHELASIPVQALG
AVFCDASQYRSQVKAALDFLIDGF

Nucleotide

• Length: 315 bp

>T154607 NZ_CP068155:2971040-2971336 [Escherichia coli]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCCCTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA

Antitoxin

Protein

• Length: 79 a.a.
• Molecular weight: 8934.00 Da
• Isoelectric Point: 7.1672

>AT154607 WP_010305008.1 NZ_CP051652:c3032669-3032433 [Pectobacterium carotovorum]
MTAKPRNTQSVTITVERALLVRAREAGINLSATLSTALDAELRRHEAKKWQEENREALAALNRFHDEQGCFSDEYRTF

Nucleotide

• Length: 237 bp

>AT154607 NZ_CP068155:2971338-2971733 [Escherichia coli]
ATGAAATGTCCGGTTTGCCACCAGGGAGAAATGGTTTCTGGCATTAAAGATATTCCATACACCTTCCGTGGACGAAAAAC
AGTATTGAAAGGTATCCACGGTTTATATTGTGTCCATTGCGAAGAGAGCATCATGAATAAAGAAGAGTCAGATGCTTTCA
TGGCGCAAGTAAAGGCATTTCGGGCTTCGGTGAATGCCGAAACAGTGGCACCTGAATTTATAGTGAAGGTTCGAAAAAAG
CTCTCTCTTACCCAAAAAGAGGCAAGCGAAATTTTTGGGGGAGGTGTAAATGCGTTTTCGCGTTACGAAAAAGGCAATGC
CCAACCTCATCCTTCCACAATCAAACTTTTACGTGTTCTGGATAAGCATCCAGAACTATTGAATGAAATCCGTTAA