Detailed information of TA system TA154601

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): EcnAB/-
• Location: 4000846..4001210
• Replicon: chromosome
• Accession: NZ_CP051651
• Organism: Xanthomonas campestris pv. badrii strain NEB122

Toxin (Protein)

• Gene name: EcnB
• Uniprot ID: -
• Locus tag: HG421_RS17000
• Protein ID: WP_104587691.1
• Coordinates: 4000846..4000980 (-)
• Length: 45 a.a.

Antitoxin (Protein)

• Gene name: EcnA
• Uniprot ID: Q3BN31
• Locus tag: HG421_RS17005
• Protein ID: WP_011348912.1
• Coordinates: 4001058..4001210 (-)
• Length: 51 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HG421_RS16985	3997637..3998575	-	939	WP_169707381.1	MBL fold metallo-hydrolase	-
HG421_RS16990	3998974..4000263	-	1290	WP_169707382.1	tryptophan--tRNA ligase	-
HG421_RS16995	4000417..4000626	-	210	WP_029221526.1	CsbD family protein	-
HG421_RS17000	4000846..4000980	-	135	WP_104587691.1	entericidin A/B family lipoprotein	Toxin
HG421_RS17005	4001058..4001210	-	153	WP_011348912.1	entericidin A/B family lipoprotein	Antitoxin
HG421_RS17010	4001320..4002243	-	924	WP_169707383.1	arginase	-
HG421_RS17015	4002565..4003017	+	453	WP_169707384.1	roadblock/LC7 domain-containing protein	-
HG421_RS17020	4003086..4003445	+	360	WP_169707385.1	roadblock/LC7 domain-containing protein	-
HG421_RS17025	4003540..4004460	+	921	WP_169707386.1	hypothetical protein	-
HG421_RS17030	4004457..4004996	+	540	WP_169707387.1	GTPase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Entericidin A/B (23-42)

Antitoxin

• Entericidin A/B (23-42)

Sequences

Toxin

Protein

• Length: 45 a.a.
• Molecular weight: 4505.29 Da
• Isoelectric Point: 9.4135

>T154601 WP_104587691.1 NZ_CP051651:c4000980-4000846 [Xanthomonas campestris pv. badrii]
MKRAIVLLVLSVFSVGMLSGCNTVAGAGKDVQGAGEKVEDAARR

Nucleotide

• Length: 135 bp

>T154601 NZ_CP068155:c1549351-1548977 [Escherichia coli]
ATGAAAACATTACCCGATACACACGTACGGGAGGCATCGAGCTGCCCGTCTCCCGTCACCATCTGGCAGACTCTGCTCTC
CCGACTACTGGGCCAGCATTACGGCCTTACACTGAATGACACACCGTTCGCCGATGAACGTGTGATTGAGCAGCATATTG
AAGCTGGCATTTCACTGTGTGATGCGGTGAATTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCACTTGTCCCCGCTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGCATCCGGAGAAACGATGA

Antitoxin

Protein

• Length: 51 a.a.
• Molecular weight: 5123.06 Da
• Isoelectric Point: 8.2782

>AT154601 WP_011348912.1 NZ_CP051651:c4001210-4001058 [Xanthomonas campestris pv. badrii]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGDKVEKTAEKCSDGKC

Nucleotide

• Length: 153 bp

>AT154601 NZ_CP068155:c1549809-1549441 [Escherichia coli]
GTGTCAGACACACTTTCCGGGACAACGCATCCCGATGACAATGACGACCATCCCTGGTGGAGACTACCCTGCACAGTGAC
GCCCTGTTTCGGCGCCCGTCTGGTGCAGGAGGGTAACCGCCTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCTGT
TCAGCGATGCAGATGCGTACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAGGTCTGACCTGCAAAGCTGACACTCTCGGTAGCGG
TGGTTACGTTTATCTGGCTGTTTATCCGACGCCCGAAACGAAAAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A3G2W7I0