154600

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3226512..3227290 Replicon chromosome
Accession NZ_CP051651
Organism Xanthomonas campestris pv. badrii strain NEB122

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag HG421_RS13620 Protein ID WP_169706828.1
Coordinates 3226799..3227290 (+) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag HG421_RS13615 Protein ID WP_169706827.1
Coordinates 3226512..3226802 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HG421_RS13605 3225156..3225641 + 486 WP_169706825.1 hypothetical protein -
HG421_RS13610 3226036..3226482 + 447 WP_169706826.1 type I toxin-antitoxin system SymE family toxin -
HG421_RS13615 3226512..3226802 + 291 WP_169706827.1 DUF1778 domain-containing protein Antitoxin
HG421_RS13620 3226799..3227290 + 492 WP_169706828.1 GNAT family N-acetyltransferase Toxin
HG421_RS13625 3227564..3227749 + 186 WP_169706829.1 hypothetical protein -
HG421_RS13630 3227746..3228048 + 303 WP_169706830.1 type II toxin-antitoxin system RelE/ParE family toxin -
HG421_RS13635 3228186..3229520 - 1335 WP_169706831.1 HAMP domain-containing histidine kinase -
HG421_RS13640 3229513..3230190 - 678 WP_003490678.1 response regulator transcription factor -
HG421_RS13645 3230217..3230693 - 477 WP_169708197.1 hypothetical protein -
HG421_RS13650 3230872..3231789 - 918 WP_169706832.1 30S ribosomal protein S6--L-glutamate ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(67-144)

Antitoxin

Vibrio phage ICP1, Orf50

(14-88)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17705.53 Da        Isoelectric Point: 9.8714

>T154600 WP_169706828.1 NZ_CP051651:3226799-3227290 [Xanthomonas campestris pv. badrii]
VTVSAPEPLMAHHRLEPFASGVESLDHWLKRRALKNQATGASRTFVACAYDRVVAYYALASSAVAVDATPGRFHRNMPDP
IPVVVLGRLAVDRSLHGRGFGRALVRDAGKRILHAADTIGIRGLLVHALSADAKMFYERVGFEPSPLDPMLLVVTLEDLK
ASL

Download         Length: 492 bp

>T154600 NZ_CP068155:c1513311-1513024 [Escherichia coli]
ATGCCAATGGAGTTTGAATGGGATGAAAACAAGGCCAAAAGTAATCGGGTGAAACATGGCATCCGCTTTGAAGATGCGGT
GTTATTGTTTGATGATCCACAACATTTGTCACAGCAAGAACGCATAGAAAACGGTGAGTATCGCTGGCAGACAATCGGCC
TGGTTTACGGCATCGTGGTTATTCTGGTTGCGCATACCATCCGTTTCGAAAGCGGAAATGAAATTATTCGAATCATCAGT
GCACGAAAAGCAGATCGTAAAGAGAGGAATCGCTATGAGCATGGTTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10660.25 Da        Isoelectric Point: 10.5480

>AT154600 WP_169706827.1 NZ_CP051651:3226512-3226802 [Xanthomonas campestris pv. badrii]
MSTPNTTPGKRETLNIRIKPEERSLIDRAAKARGKNRTDFMLDAARLAAEEALLDQTLIAASPDAYAAFLARLDMPPQPN
ARLRKTMQTPAPWEKG

Download         Length: 291 bp

>AT154600 NZ_CP068155:c1513037-1512735 [Escherichia coli]
ATGAGCATGGTTAAACATAAACGAGGGACCTCCTCTACACTCGATGTGCAGCATGAGGCCGAACTGAAGGCGCTGGCGAA
TAAATCCGACGAAGATATTGATTACAGTGATATCCCACCTTCCAGCGATGAGCAATGGTCTAACGCCGAACGCGGTAAGT
TTTATCGGCCATTGAAAACTCAGGCTTCGGTGCGTATTGATGCTGATGTGATGGAATGGTTGAAGCGACCAGGTAAAGGC
TATCAAACTCGCCTGAACGCAATTTTACGTGAAGCGATGCTGCGCGATCAGAACAAAAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References