Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 327291..327831 Replicon chromosome
Accession NZ_CP051642
Organism Avibacterium paragallinarum strain ADL-AP01

Toxin (Protein)


Gene name relE Uniprot ID A0A3G8VZS8
Locus tag HHJ56_RS01760 Protein ID WP_035688134.1
Coordinates 327541..327831 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A3G8W1I3
Locus tag HHJ56_RS01755 Protein ID WP_035688131.1
Coordinates 327291..327551 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HHJ56_RS01730 323417..324628 + 1212 WP_035688123.1 tyrosine-type recombinase/integrase -
HHJ56_RS01735 324859..325008 - 150 WP_156127747.1 hypothetical protein -
HHJ56_RS01740 325288..325494 + 207 WP_035688126.1 AlpA family phage regulatory protein -
HHJ56_RS01745 325498..326175 + 678 WP_035688128.1 hypothetical protein -
HHJ56_RS01750 326187..327152 + 966 WP_035688129.1 P2 family phage major capsid protein -
HHJ56_RS01755 327291..327551 + 261 WP_035688131.1 stability protein StbD Antitoxin
HHJ56_RS01760 327541..327831 + 291 WP_035688134.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HHJ56_RS01765 327873..328973 + 1101 WP_051128101.1 hypothetical protein -
HHJ56_RS01770 329137..329352 + 216 WP_035688136.1 helix-turn-helix domain-containing protein -
HHJ56_RS01775 329363..329668 + 306 WP_035688139.1 hypothetical protein -
HHJ56_RS01780 329772..330344 + 573 WP_051128102.1 ash family protein -
HHJ56_RS01785 330337..330567 + 231 WP_035688141.1 hypothetical protein -
HHJ56_RS01790 330560..330829 + 270 WP_035688144.1 hypothetical protein -
HHJ56_RS01795 330834..331058 + 225 WP_035688166.1 hypothetical protein -
HHJ56_RS01800 331058..331399 + 342 WP_035688146.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11399.31 Da        Isoelectric Point: 10.6318

>T154582 WP_035688134.1 NZ_CP051642:327541-327831 [Avibacterium paragallinarum]
MTYKLSFDKRALKEWHKLGDTLRQQFKAKLIERLENPHVLSDKLHGYQTLYKIKLRSAGYRLVYDVNDNEIRVIVLSVGK
REHLQAYKKALSRKAQ

Download         Length: 291 bp

>T154582 NZ_CP068151:c2963638-2963369 [Pseudomonas fluorescens]
ATGCTGATTGAGTGGTCGCCCGCAGCGCGGGTAGAACTCCGGCAAATTATTGAGTACCTCAGTCATCGTAATCCTGTAGC
AGCGCTTGAGCTTAAGCGATCAATCGAAGCTTCAGTGCTTGCCCTCTCGCGCAGACCCCATCTTTACCGCCCCGGCAGAA
TCGGCGGAACACGAGAGATGGTGGTACATCCGAATTATCTGGTTGTATACAAAGTGACAGACAATATTCGGATTCTCTCG
GTTTTACACGCACGCCAGCGATATCCTTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9550.98 Da        Isoelectric Point: 4.1813

>AT154582 WP_035688131.1 NZ_CP051642:327291-327551 [Avibacterium paragallinarum]
MAIQQILTRHTASISDLKKNPMGIVSEGTEQEGAIAILNRNEPVFYCVNPCLFAVIQEILEDKELGELATQRLATLDPVE
VRLDDL

Download         Length: 261 bp

>AT154582 NZ_CP068151:c2963816-2963628 [Pseudomonas fluorescens]
ATGGACACTTCCTTTTCCTCAGGTATCCAAGCAGATATCGAAGAGCAGGCTGACAGCTACGACCGCTGGTTTCGCGCGAG
AGTGCAGGCCGCTCTTGATGACCCAAGCCCTGGCATTCCTCACGACGAGGTGATGGCCGAGATGCAAGCGCTGATCGAAT
CTAAACTCAAGAAAGGCGATGCTGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G8VZS8

Antitoxin

Source ID Structure
AlphaFold DB A0A3G8W1I3

References