Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 517083..517351 | Replicon | chromosome |
| Accession | NZ_CP051609 | ||
| Organism | Escherichia coli O25b:H4-ST131 strain 2019_APHA | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 517121..517223 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 517083..517351 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HHM37_RS02505 | 514241..515680 | + | 1440 | WP_001296139.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| HHM37_RS02510 | 515797..516033 | + | 237 | WP_001295499.1 | DUF1480 family protein | - |
| HHM37_RS02515 | 516138..516329 | + | 192 | WP_001296140.1 | YebW family protein | - |
| HHM37_RS02520 | 516330..516986 | - | 657 | WP_000812745.1 | protein-serine/threonine phosphatase | - |
| - | 517083..517351 | + | 269 | - | - | Antitoxin |
| - | 517121..517223 | - | 103 | - | - | Toxin |
| HHM37_RS02525 | 517381..517722 | - | 342 | WP_000976472.1 | YebY family protein | - |
| HHM37_RS02530 | 517735..518607 | - | 873 | WP_000879317.1 | copper homeostasis membrane protein CopD | - |
| HHM37_RS02535 | 518611..518985 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| HHM37_RS02540 | 519124..519354 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| HHM37_RS02545 | 519456..520112 | + | 657 | WP_000011664.1 | carbon-nitrogen hydrolase family protein | - |
| HHM37_RS02550 | 520136..520798 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T154431 NZ_CP051609:c517223-517121 [Escherichia coli O25b:H4-ST131]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 269 bp
>AT154431 NZ_CP051609:517083-517351 [Escherichia coli O25b:H4-ST131]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT
