154415

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1413432..1414095 Replicon chromosome
Accession NZ_CP051548
Organism Phytobacter diazotrophicus strain UAEU22

Toxin (Protein)


Gene name cptA Uniprot ID A0A348D8P9
Locus tag HHA33_RS06740 Protein ID WP_039077972.1
Coordinates 1413679..1414095 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A348D8P8
Locus tag HHA33_RS06735 Protein ID WP_039077973.1
Coordinates 1413432..1413698 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HHA33_RS06710 1408613..1410046 - 1434 WP_108700659.1 6-phospho-beta-glucosidase -
HHA33_RS06715 1410168..1410896 - 729 WP_039077977.1 MurR/RpiR family transcriptional regulator -
HHA33_RS06720 1410949..1411260 + 312 WP_039077976.1 N(4)-acetylcytidine aminohydrolase -
HHA33_RS06725 1411423..1412082 + 660 WP_039077975.1 hemolysin III family protein -
HHA33_RS06730 1412199..1413182 - 984 WP_071196007.1 tRNA-modifying protein YgfZ -
HHA33_RS06735 1413432..1413698 + 267 WP_039077973.1 FAD assembly factor SdhE Antitoxin
HHA33_RS06740 1413679..1414095 + 417 WP_039077972.1 protein YgfX Toxin
HHA33_RS06745 1414098..1414619 - 522 WP_039077971.1 flavodoxin FldB -
HHA33_RS06750 1414721..1415617 + 897 WP_039077970.1 site-specific tyrosine recombinase XerD -
HHA33_RS06755 1415642..1416355 + 714 WP_039077969.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
HHA33_RS06760 1416361..1418094 + 1734 WP_039077968.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16438.33 Da        Isoelectric Point: 11.4778

>T154415 WP_039077972.1 NZ_CP051548:1413679-1414095 [Phytobacter diazotrophicus]
VVLWQSDIRVSWRSQWLSLLLHGLMAAFVLLLPWPLSYTPLWLLLLSLVVFDSVRSQRRINACQGEIKLLMDARLRWQGV
EWEIVGTPWMLNIGMILRLRREKDGRRQHLWLAADSMDAQEWRDLRRLISQQSAQRQH

Download         Length: 417 bp

>T154415 NZ_CP068041:c2976089-2975835 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCTCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCTACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10555.03 Da        Isoelectric Point: 6.2199

>AT154415 WP_039077973.1 NZ_CP051548:1413432-1413698 [Phytobacter diazotrophicus]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDDDKRVFVRLLQSDDPDLFNWLMNHGKPQDEALQRMIQLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT154415 NZ_CP068041:c2976337-2976086 [Escherichia coli]
ATGCGTACAATTAGTTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A348D8P9

Antitoxin

Source ID Structure
AlphaFold DB A0A348D8P8

References