Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 879852..880428 Replicon chromosome
Accession NZ_CP051537
Organism Helicobacter pylori strain LIM-005

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HG578_RS04140 Protein ID WP_187924483.1
Coordinates 879852..880124 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HG578_RS04145 Protein ID WP_187915350.1
Coordinates 880138..880428 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HG578_RS04115 875310..876383 - 1074 WP_202135189.1 glycosyltransferase family 8 protein -
HG578_RS04120 876494..877261 - 768 WP_000242348.1 ABC transporter ATP-binding protein -
HG578_RS04125 877261..878241 - 981 WP_000921476.1 iron ABC transporter permease -
HG578_RS04130 878234..879082 - 849 WP_202134465.1 SDR family oxidoreductase -
HG578_RS04135 879222..879746 + 525 WP_001135604.1 acyl-CoA thioesterase -
HG578_RS04140 879852..880124 - 273 WP_187924483.1 type II toxin-antitoxin system YafQ family toxin Toxin
HG578_RS04145 880138..880428 - 291 WP_187915350.1 hypothetical protein Antitoxin
HG578_RS04150 881338..883566 - 2229 WP_202134466.1 outer membrane beta-barrel protein -
HG578_RS04165 884351..884881 + 531 WP_202134467.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10455.36 Da        Isoelectric Point: 8.4839

>T154399 WP_187924483.1 NZ_CP051537:c880124-879852 [Helicobacter pylori]
MLMIETSKKFDKDLKILVKNGFDLKLLYEVVGNLATEQPLEPKYKDHPLKGALKDFRECYLKPDLLLVCQIKKQENTLFL
VRLGSHSESF

Download         Length: 273 bp

>T154399 NZ_CP068040:c60837-60562 [Escherichia coli]
ATGGAACTGAAGTGGACCAGTAAGGCGCTTTCTGATTTGGCGCGGTTATATGATTTTCTGGTGCTGGCCAGTAAACCTGC
TGCCGCCAGAACGGTACAGTCCCTGACACAGGCACCGGTCATTCTGTTAACTCATCCACGTATGGGAGAACAGTTGTTTC
AGTTTGAACCCAGGGAGGTCAGACGGATTTTTGCTGGCGAGTACGAAATCCGTTACGAACTTAATGGCCAGACTATTTAT
GTATTGCGCCTGTGGCACACACGAGAAAACAGGTAG

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11447.33 Da        Isoelectric Point: 10.2195

>AT154399 WP_187915350.1 NZ_CP051537:c880428-880138 [Helicobacter pylori]
MPNTTAKKDYTKYSEKQLFNFLNSIKTKQKIALEKLKEIQAQKQRIKKALQFKALYLTENGYTIEEEREILARAKDTKNR
LCFKSIEDFKKHCENL

Download         Length: 291 bp

>AT154399 NZ_CP068040:c61121-60837 [Escherichia coli]
ATACAAATGAAAAACAATACCGCACAGGCAACAAAAGTCATTACCGCGCATGTGCCATTACCTATGGCTGATAAAGTCGA
CCAGATGGCCGCCAGGCTGGAACGCTCCCGGGGCTGGGTTATCAAACAGGCGCTTTCTGCATGGCTTGCCCAAGAGGAGG
AGCGTAATCGCCTGACGCTGGAAGCCCTGGACGATGTGACATCCGGACAGGTTATCGACCATCAGGCTGTACAGGCCTGG
GCGGACAGTCTCAGTACTGACAATCCGTTACCGGTGCCCCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References