Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 347760..348336 Replicon chromosome
Accession NZ_CP051533
Organism Helicobacter pylori strain LIM-010

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HG583_RS01680 Protein ID WP_187924483.1
Coordinates 347760..348032 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HG583_RS01685 Protein ID WP_187915350.1
Coordinates 348046..348336 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HG583_RS01645 342886..343767 + 882 WP_001040390.1 polysaccharide deacetylase -
HG583_RS01650 343814..344200 + 387 WP_202143159.1 hypothetical protein -
HG583_RS01655 344200..345165 + 966 WP_202143160.1 GTP-binding protein -
HG583_RS01660 345171..346316 - 1146 WP_187924603.1 YbfB/YjiJ family MFS transporter -
HG583_RS01665 346811..347080 - 270 Protein_322 virulence associated protein VapD -
HG583_RS01670 347218..347448 + 231 WP_080025421.1 hypothetical protein -
HG583_RS01675 347461..347712 - 252 WP_202142600.1 hypothetical protein -
HG583_RS01680 347760..348032 - 273 WP_187924483.1 type II toxin-antitoxin system YafQ family toxin Toxin
HG583_RS01685 348046..348336 - 291 WP_187915350.1 hypothetical protein Antitoxin
HG583_RS01690 349186..351423 - 2238 WP_202143161.1 outer membrane beta-barrel protein -
HG583_RS01695 351710..352465 - 756 WP_202143162.1 HugZ family heme oxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10455.36 Da        Isoelectric Point: 8.4839

>T154389 WP_187924483.1 NZ_CP051533:c348032-347760 [Helicobacter pylori]
MLMIETSKKFDKDLKILVKNGFDLKLLYEVVGNLATEQPLEPKYKDHPLKGALKDFRECYLKPDLLLVCQIKKQENTLFL
VRLGSHSESF

Download         Length: 273 bp

>T154389 NZ_CP068035:c4176003-4175596 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11447.33 Da        Isoelectric Point: 10.2195

>AT154389 WP_187915350.1 NZ_CP051533:c348336-348046 [Helicobacter pylori]
MPNTTAKKDYTKYSEKQLFNFLNSIKTKQKIALEKLKEIQAQKQRIKKALQFKALYLTENGYTIEEEREILARAKDTKNR
LCFKSIEDFKKHCENL

Download         Length: 291 bp

>AT154389 NZ_CP068035:c4176250-4175984 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References