154384

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ygfYX/Cpta(toxin)
Location 1368544..1369213 Replicon chromosome
Accession NZ_CP051529
Organism Shewanella baltica strain 11FHM2

Toxin (Protein)


Gene name ygfX Uniprot ID -
Locus tag HHE93_RS05885 Protein ID WP_259215202.1
Coordinates 1368773..1369213 (+) Length 147 a.a.

Antitoxin (Protein)


Gene name ygfY Uniprot ID -
Locus tag HHE93_RS05880 Protein ID WP_006080770.1
Coordinates 1368544..1368792 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HHE93_RS05855 (HHE93_05895) 1364200..1365009 + 810 WP_259215198.1 prolipoprotein diacylglyceryl transferase -
HHE93_RS05860 (HHE93_05900) 1365006..1365800 + 795 WP_006085062.1 thymidylate synthase -
HHE93_RS05865 (HHE93_05905) 1365918..1367087 + 1170 WP_006080767.1 Na+/H+ antiporter NhaA -
HHE93_RS05870 (HHE93_05910) 1367090..1367476 + 387 WP_006080768.1 hypothetical protein -
HHE93_RS05875 (HHE93_05915) 1367550..1368458 + 909 WP_259215201.1 transcriptional activator NhaR -
HHE93_RS05880 (HHE93_05920) 1368544..1368792 + 249 WP_006080770.1 succinate dehydrogenase assembly factor 2 Antitoxin
HHE93_RS05885 (HHE93_05925) 1368773..1369213 + 441 WP_259215202.1 protein YgfX Toxin
HHE93_RS05890 (HHE93_05930) 1369282..1370895 - 1614 WP_006080772.1 L-aspartate oxidase -
HHE93_RS05895 (HHE93_05935) 1371086..1371664 + 579 WP_006080773.1 RNA polymerase sigma factor RpoE -
HHE93_RS05900 (HHE93_05940) 1371706..1372332 + 627 WP_006080774.1 RseA family anti-sigma factor -
HHE93_RS05905 (HHE93_05945) 1372345..1373277 + 933 WP_259215204.1 MucB/RseB C-terminal domain-containing protein -
HHE93_RS05910 (HHE93_05950) 1373288..1373761 + 474 WP_006080776.1 SoxR reducing system RseC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(7-135)

Antitoxin

Flavinator of succinate dehydrogenase

(7-77)


Sequences

Toxin        


Download         Length: 147 a.a.        Molecular weight: 17355.47 Da        Isoelectric Point: 7.7165

>T154384 WP_259215202.1 NZ_CP051529:1368773-1369213 [Shewanella baltica]
VEDRHHSFILKASFDQRLSLVVFICVCSSSFLLWPQSDNLALSLLKYLFILLVCVFLLSQMWRLQHWRLDFVLSDKGEGR
LSTGEHFQVLKRTWVTPFVCLMYIEVDTQLRLLMVWADMLDDNDYRHLCRLLLRAKIQQTKPHTEI

Download         Length: 441 bp

>T154384 NZ_CP068035:c3175627-3175373 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9723.36 Da        Isoelectric Point: 4.4929

>AT154384 WP_006080770.1 NZ_CP051529:1368544-1368792 [Shewanella baltica]
MELMNIARVRWACRRGMLELDVLFQPFVENFYQEMSDEDKTVFIRLLECEDPELFAWFMGHEVCPDAELARMVVKVRGRP
AP

Download         Length: 249 bp

>AT154384 NZ_CP068035:c3175875-3175624 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References