Detailed information of TA system TA154371

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): shpA-AbkA/BrnT_toxin-BrnA
• Location: 4329133..4329708
• Replicon: chromosome
• Accession: NZ_CP051516
• Organism: Paraburkholderia aromaticivorans strain AR20-38

Toxin (Protein)

• Gene name: shpA
• Uniprot ID: -
• Locus tag: HF916_RS47885
• Protein ID: WP_168795494.1
• Coordinates: 4329430..4329708 (-)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: AbkA
• Uniprot ID: -
• Locus tag: HF916_RS47880
• Protein ID: WP_168795875.1
• Coordinates: 4329133..4329390 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HF916_RS47860	4324321..4325073	+	753	WP_168795490.1	5-oxoprolinase subunit PxpA	-
HF916_RS47865	4325338..4326087	+	750	WP_168795491.1	DUF969 domain-containing protein	-
HF916_RS47870	4326084..4327040	+	957	WP_168795492.1	DUF979 domain-containing protein	-
HF916_RS47875	4327255..4329060	+	1806	WP_168795493.1	tetratricopeptide repeat protein	-
HF916_RS47880	4329133..4329390	-	258	WP_168795875.1	BrnA antitoxin family protein	Antitoxin
HF916_RS47885	4329430..4329708	-	279	WP_168795494.1	BrnT family toxin	Toxin
HF916_RS47890	4329908..4331071	-	1164	WP_168795495.1	TraB/GumN family protein	-
HF916_RS47895	4331064..4332083	-	1020	WP_168795496.1	ABC transporter ATP-binding protein	-
HF916_RS47900	4332080..4333084	-	1005	WP_168795497.1	ABC transporter ATP-binding protein	-
HF916_RS47905	4333085..4334002	-	918	WP_168795498.1	ABC transporter permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (5-82)

Antitoxin

• BrnA antitoxin of type II toxin-antitoxin system (24-77)

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 10982.53 Da
• Isoelectric Point: 6.6443

>T154371 WP_168795494.1 NZ_CP051516:c4329708-4329430 [Paraburkholderia aromaticivorans]
VLFEWDEIKNQINIRKHGIDFQDAIDVFNHPLLTALDQREDYGEDRWVAMGWIASIVGIVVYVERVEDVVRIISARKATR
HEVKHYKQRVWH

Nucleotide

• Length: 279 bp

>T154371 NZ_CP068034:c5679920-5679630 [Pseudomonas syringae]
ATGACCTATAACCTCGAATTCGATGCGCGGGCTTTAAAGGACTGGCACAAATTAGGGGATACCGTGCGTCAGCAGCTCAA
GAAAAAGCTGGCTACGATTCTGGTTGCTCCGCGTGTTGAAGCCAATCGTCTGCATGCATTGCCTGACTGCTACAAAATCA
AACTGCGCAGTAGCGGCTATCGGCTGGTTTATCAGGTTATTGATAAAGAGGTTGTGGTCTTCGTGGTTGCTGTGGACAAG
CGTGAGCGAGAGGAGGTTTACCGTAAAGCGGCTGATCGGTTGGGTAGGTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9876.23 Da
• Isoelectric Point: 9.6912

>AT154371 WP_168795875.1 NZ_CP051516:c4329390-4329133 [Paraburkholderia aromaticivorans]
MVKASGTDWKRLAKTDDAQIDTSDVPELGDDFFQRAELHVPPKQAVTMRLDADVLNWFKEQGQGYQTRINKLLRAYMLAQ
QRRRP

Nucleotide

• Length: 258 bp

>AT154371 NZ_CP068034:c5680149-5679910 [Pseudomonas syringae]
ATGGCGTCTATCAACGTTCGTATCGACGACGATCTCAAAGCGCGTGCTTACCTTGAGCTGGAAAAGCTTGGCGTCACCCC
CTCGGAGTTGCTGCGCCAAACCCTGCAGTACGTAGCTGAGCGTGGCCAGCTGCCCTTCAAGACAGTTCTGATGACAGAGG
AAGACGAAGCGCTGTTGGCAACTGTGCGCGAGCGCCTTGCAGCTCCGCAGCGGGTCAAGGTTTCACTGGATGACCTATAA