Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 893868..894501 Replicon chromosome
Accession NZ_CP051511
Organism Helicobacter pylori strain ASHA-006

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HGK51_RS04350 Protein ID WP_202170482.1
Coordinates 893868..894134 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HGK51_RS04355 Protein ID WP_202170483.1
Coordinates 894115..894501 (-) Length 129 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HGK51_RS04330 890539..891306 - 768 WP_015086905.1 ABC transporter ATP-binding protein -
HGK51_RS04335 891306..892286 - 981 WP_202170480.1 iron ABC transporter permease -
HGK51_RS04340 892279..893121 - 843 WP_202170481.1 SDR family oxidoreductase -
HGK51_RS04345 893262..893786 + 525 WP_001120215.1 acyl-CoA thioesterase -
HGK51_RS04350 893868..894134 - 267 WP_202170482.1 type II toxin-antitoxin system YafQ family toxin Toxin
HGK51_RS04355 894115..894501 - 387 WP_202170483.1 hypothetical protein Antitoxin
HGK51_RS04360 894814..897054 - 2241 WP_202170484.1 outer membrane beta-barrel protein -
HGK51_RS04375 897386..898012 + 627 WP_202170485.1 hypothetical protein -
HGK51_RS04380 897963..899075 - 1113 WP_202170486.1 hydrogenase formation protein HypD -
HGK51_RS04385 899094..899330 - 237 WP_202170487.1 HypC/HybG/HupF family hydrogenase formation chaperone -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10289.14 Da        Isoelectric Point: 9.6292

>T154358 WP_202170482.1 NZ_CP051511:c894134-893868 [Helicobacter pylori]
VLKLNLKKSFQKDFDKLLLNGFDDSVLNKVILSLRKKEPLDPQFKDHALKGNWKPFRECHIKADILLVYLVKDDELVLLR
LGSHSELF

Download         Length: 267 bp

>T154358 NZ_CP068031:824590-824952 [Staphylococcus saccharolyticus]
ATGATTAGAAGAGGAGATGTTTATTTAGCGGATTTATCACCAGTCCAAGGGTCTGAACAAGGGGGAGTAAGACCTGTTGT
TATCATTCAAAATGATACTGGTAATAAATATAGTCCAACAGTAATTGTTGCTGCAATTACAGGCAGGATTAATAAAGCGA
AAATACCAACCCACGTAGAAATTGAAAAGAAAAAATACAAATTAGACAAGGACTCCGTTATATTGCTTGAACAGATTAGA
ACATTAGATAAGAAGCGTTTAAAAGAAAAGCTGACTTATTTATCTGAAAGCAAGATGAAAGAAGTTGATAACGCGCTAGA
CATTAGTCTAGGTCTACATAACTTTGATCAACAAAAATCATAG

Antitoxin


Download         Length: 129 a.a.        Molecular weight: 14916.85 Da        Isoelectric Point: 5.3469

>AT154358 WP_202170483.1 NZ_CP051511:c894501-894115 [Helicobacter pylori]
MPNSPTKKDCTQYSEKQLFNLINQLEQKIKKMQNDRASFKEKMAKELEKRDQNFKDKIDALNELLQKISQVFDDKRDCCL
GHEIPNLETQQAMRDALNGENLETDLIVEDFSSYSDERKKALGVKTQS

Download         Length: 387 bp

>AT154358 NZ_CP068031:824423-824593 [Staphylococcus saccharolyticus]
ATGTTATCTTTTAATCAAACTAGAACTAACAGTCTTGAACAATCGTTGAAAGAGGGCTATTCACAAATGGCCGATTTAAA
CCTCTCCCTAGCAACGGAAGCTTTTCCTATTGAATGTGAAGCTTGCGATTGTAATGAAACATATTTGACTTCTAATTCAC
AAAGTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References