Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 919662..920232 Replicon chromosome
Accession NZ_CP051510
Organism Helicobacter pylori strain ASHA-008

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HG557_RS04370 Protein ID WP_202135255.1
Coordinates 919662..919934 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HG557_RS04375 Protein ID WP_202135257.1
Coordinates 919921..920232 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HG557_RS04350 916332..917100 - 769 Protein_852 ABC transporter ATP-binding protein -
HG557_RS04355 917100..918080 - 981 WP_202165745.1 iron ABC transporter permease -
HG557_RS04360 918073..918915 - 843 WP_202165746.1 SDR family oxidoreductase -
HG557_RS04365 919056..919580 + 525 WP_001120215.1 acyl-CoA thioesterase -
HG557_RS04370 919662..919934 - 273 WP_202135255.1 type II toxin-antitoxin system YafQ family toxin Toxin
HG557_RS04375 919921..920232 - 312 WP_202135257.1 hypothetical protein Antitoxin
HG557_RS04380 920531..922768 - 2238 WP_202171532.1 outer membrane beta-barrel protein -
HG557_RS04395 923218..923739 + 522 WP_202165750.1 hypothetical protein -
HG557_RS04400 923690..924802 - 1113 WP_202165751.1 hydrogenase formation protein HypD -
HG557_RS04405 924821..925057 - 237 WP_078284132.1 HypC/HybG/HupF family hydrogenase formation chaperone -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10649.63 Da        Isoelectric Point: 9.7265

>T154356 WP_202135255.1 NZ_CP051510:c919934-919662 [Helicobacter pylori]
MLMIETSKKFDKDLKILVKNGFDLKFLYKVVENLAKEQPLDPKYKDHPLKGTLKDFRECHLKPDLLLVYQVKKQENTLFL
VRLGSHSELF

Download         Length: 273 bp

>T154356 NZ_CP068029:1866441-1866629 [Staphylococcus saccharolyticus]
ATGAGTTTACATTTTTATATCCTATTATGGCTTGCCATACTGTTTATTATTGCAGGAACTATCTTATTAATTACAATGCT
AAAAACTAAAAAAGAAGAAAGAAAAGAATCCTACTTAGGCTTTACAGTCATCTTCTTAATCTTTGGTATTGCCATACTTA
TCTACACGCTTATATTTGGAATTTTGTAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 12302.17 Da        Isoelectric Point: 10.3492

>AT154356 WP_202135257.1 NZ_CP051510:c920232-919921 [Helicobacter pylori]
MPNSPTKKDFTRYSEKQLFNFLNSIKTKQKRALEKLKEIQAQKQRIKKALQFKALHLTENGYTIEEEREILARAKDTKNH
LCFKSVEDFKKHCENLRFKNADD

Download         Length: 312 bp

>AT154356 NZ_CP068029:1866153-1866410 [Staphylococcus saccharolyticus]
ATGAAACTAATTAGAATAAATGTAATTAACGTGATATTAACTATACTATTTATGGCTTTTAACGTACTCATTACCTACAA
CGAGAATATTGATAACAATTTGTGGTTAGTACCAGGATTAATCATTTGTGGTATTACTTTACTTACAAGTTTAACAATAG
CTATTGTGTATACTGATTTATTTAGTGAAATTTTATTTTTTATCAATATCATTTTAGCACTATATTATATCTATCCTATT
CTTTATGAGTTCATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References