Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 459033..459657 Replicon chromosome
Accession NZ_CP051509
Organism Helicobacter pylori strain ASHA-009

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HG558_RS02205 Protein ID WP_202166921.1
Coordinates 459391..459657 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HG558_RS02200 Protein ID WP_202166920.1
Coordinates 459033..459410 (+) Length 126 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HG558_RS02170 454168..454404 + 237 WP_000335458.1 HypC/HybG/HupF family hydrogenase formation chaperone -
HG558_RS02175 454407..455519 + 1113 WP_000115669.1 hydrogenase formation protein HypD -
HG558_RS02180 455470..455991 - 522 WP_202166918.1 hypothetical protein -
HG558_RS02195 456440..458662 + 2223 WP_202166919.1 outer membrane beta-barrel protein -
HG558_RS02200 459033..459410 + 378 WP_202166920.1 hypothetical protein Antitoxin
HG558_RS02205 459391..459657 + 267 WP_202166921.1 type II toxin-antitoxin system YafQ family toxin Toxin
HG558_RS02210 459741..460265 - 525 WP_001120216.1 acyl-CoA thioesterase -
HG558_RS02215 460406..461248 + 843 WP_202166922.1 SDR family oxidoreductase -
HG558_RS02220 461241..462221 + 981 WP_000921444.1 iron ABC transporter permease -
HG558_RS02225 462221..462988 + 768 WP_202132517.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10318.14 Da        Isoelectric Point: 8.0602

>T154355 WP_202166921.1 NZ_CP051509:459391-459657 [Helicobacter pylori]
VLKLNLKKSFQKDFDKLLLNGFDDSVLNEVILSLRKKEPLDPQFQDHALKGKWKPFRECHIKADILLVYLVKDDELILLR
LGSHSELF

Download         Length: 267 bp

>T154355 NZ_CP068029:969176-969349 [Staphylococcus saccharolyticus]
ATGTCGAATAAAAAGAATTCTAAATTAAATTATCATGAAGAAGAAAATGCAATGGTAACAGATTTAGATGATTTAAAAGA
ATTAGGTAAAGAGATGGAACATATTTCTGAGAAGAATGATGAAGATAAAGTTAATCAATCTCATGATGAGATTTGTTCTG
ATAAAACTAACTAA

Antitoxin


Download         Length: 126 a.a.        Molecular weight: 14559.49 Da        Isoelectric Point: 7.7121

>AT154355 WP_202166920.1 NZ_CP051509:459033-459410 [Helicobacter pylori]
MPNSPTKKDCTQYSEKQLFNLINQLERKIKKMQNDRASFKEKMAKELEKRDQNFKDKIDALNELLQKISQAFDNKRDCCL
GHEIPNLETQQAMRDALNKETDLIVEDFSSYSDGRKKALGVETQS

Download         Length: 378 bp

>AT154355 NZ_CP068029:968552-969151 [Staphylococcus saccharolyticus]
ATGGCAATGAACTTTAAAGTATTTGATAATAATGATAGAGTAGCAGAATACGCTGCTGATATTATTCGCAAACAATTTAA
TAATAATCCTACGACAATTGCAGGGTTTCATTTAGATAAAGAACATGCACCTGTTCTTGATGAACTTAAAAAAAATGTCG
ACTGCCATGCTGTTGATTTCAGTCAAATTAACATTTTAGATTATGATAATAATCGTTCTTACTATGAAACATTAGGAGTT
CCAGAAGGTCAAGTGTATTCAATTTCTTATGATCAAGATGCAATTGGATTTATTTCAGACAAGATGAAAACGAAAGAAAA
TAAAGGTAAACTTATTTTACAAGTATTATCAATTGATGAAAATGGAAAATTAGACGTTAATGTACGCCAAGGGTTGATGG
AAGCTAGAGAAATTTTCCTTATCATTACAGGCAGTCAAAAACGTGATGTTGTTGAAAAATTATATCGCGAGAATGGCAAA
TCTAGTTATGAACCAGCTGATTTAAAAGCACACCGTATGGTCAATGTTATTTTAGATAAAGAATCAGCAGAAGGTTTACC
TGAAGATGTTAAAGAGTACTTCACAGCGCGTTTTGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References