Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 919543..920113 Replicon chromosome
Accession NZ_CP051508
Organism Helicobacter pylori strain ASHA-010

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HG559_RS04385 Protein ID WP_202135255.1
Coordinates 919543..919815 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HG559_RS04390 Protein ID WP_202135257.1
Coordinates 919802..920113 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HG559_RS04365 916214..916981 - 768 WP_202132517.1 ABC transporter ATP-binding protein -
HG559_RS04370 916981..917961 - 981 WP_202165745.1 iron ABC transporter permease -
HG559_RS04375 917954..918796 - 843 WP_202165746.1 SDR family oxidoreductase -
HG559_RS04380 918937..919461 + 525 WP_001120215.1 acyl-CoA thioesterase -
HG559_RS04385 919543..919815 - 273 WP_202135255.1 type II toxin-antitoxin system YafQ family toxin Toxin
HG559_RS04390 919802..920113 - 312 WP_202135257.1 hypothetical protein Antitoxin
HG559_RS04395 920412..922649 - 2238 WP_202165749.1 outer membrane beta-barrel protein -
HG559_RS04410 923098..923619 + 522 WP_202165750.1 hypothetical protein -
HG559_RS04415 923570..924682 - 1113 WP_202165751.1 hydrogenase formation protein HypD -
HG559_RS04420 924701..924937 - 237 WP_078284132.1 HypC/HybG/HupF family hydrogenase formation chaperone -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10649.63 Da        Isoelectric Point: 9.7265

>T154352 WP_202135255.1 NZ_CP051508:c919815-919543 [Helicobacter pylori]
MLMIETSKKFDKDLKILVKNGFDLKFLYKVVENLAKEQPLDPKYKDHPLKGTLKDFRECHLKPDLLLVYQVKKQENTLFL
VRLGSHSELF

Download         Length: 273 bp

>T154352 NZ_CP068023:c2820614-2820360 [Pseudoalteromonas sp. GCY]
ATGAAAATCGTATCTTTTACTGAAGCTAGAAATAGTCTCAAAGCTGTTTTAGACGGTGTAGTTAATGATGCTGATACAAC
AGTTATAACACGGCGTGACTCTGAGGATGCAGTGGTTATGTCTTTAGACTACTACAATAGCCTTATGGAAACAGTGCATT
TACTACGTTCTCCTCAAAACGCTGAACACCTAAACCGTTCAATAGCACAGTACCGCGCTGGTAAAACAACAACGCGAGAG
TTAATTGATGAGTAG

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 12302.17 Da        Isoelectric Point: 10.3492

>AT154352 WP_202135257.1 NZ_CP051508:c920113-919802 [Helicobacter pylori]
MPNSPTKKDFTRYSEKQLFNFLNSIKTKQKRALEKLKEIQAQKQRIKKALQFKALHLTENGYTIEEEREILARAKDTKNH
LCFKSVEDFKKHCENLRFKNADD

Download         Length: 312 bp

>AT154352 NZ_CP068023:c2820367-2820107 [Pseudoalteromonas sp. GCY]
ATGAGTAGTTTATTGGCGTGGACTGATGACGCTTGGGATGATTACCTGTATTGGCAAACTCAAGAAAAGAAAACACTTAA
GCGCATCAATAAACTACTCAATGATGTTAAGCGCTCTCCATTTGAGGGCATCGGGAAACCTGAGGCGTTGAAAGAGAATC
TATCTGGTTTTTGGTCTCGTCGTATTGATGATACTAACAGACTTGTTTACGCAGTTGATGATCAAGCGATAACGATAATT
TCGTGTCGTTACCACTACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References