Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 957816..958440 Replicon chromosome
Accession NZ_CP051507
Organism Helicobacter pylori strain SHIM-002

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HG560_RS04510 Protein ID WP_202170233.1
Coordinates 957816..958082 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HG560_RS04515 Protein ID WP_202170234.1
Coordinates 958063..958440 (-) Length 126 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HG560_RS04490 954465..955232 - 768 WP_000242371.1 ABC transporter ATP-binding protein -
HG560_RS04495 955232..956212 - 981 WP_202132518.1 iron ABC transporter permease -
HG560_RS04500 956205..957047 - 843 WP_000504119.1 SDR family oxidoreductase -
HG560_RS04505 957188..957712 + 525 WP_001120215.1 acyl-CoA thioesterase -
HG560_RS04510 957816..958082 - 267 WP_202170233.1 type II toxin-antitoxin system YafQ family toxin Toxin
HG560_RS04515 958063..958440 - 378 WP_202170234.1 hypothetical protein Antitoxin
HG560_RS04520 958658..960889 - 2232 WP_202170235.1 outer membrane beta-barrel protein -
HG560_RS04535 961232..961858 + 627 WP_202170236.1 hypothetical protein -
HG560_RS04540 961809..962921 - 1113 WP_202170237.1 hydrogenase formation protein HypD -
HG560_RS04545 962924..963160 - 237 WP_202170238.1 HypC/HybG/HupF family hydrogenase formation chaperone -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10345.21 Da        Isoelectric Point: 9.6561

>T154350 WP_202170233.1 NZ_CP051507:c958082-957816 [Helicobacter pylori]
VLRLNLKKSFQKDFDKLLLNGFDDSVLNKVILSLRKKEPLDPQFQDHALKGKWKPFRECHIKADILLVYLVKDDELILLR
LGSHSELF

Download         Length: 267 bp

>T154350 NZ_CP068023:c2195021-2194734 [Pseudoalteromonas sp. GCY]
ATGTCAGTAAATTTTAAAGATGATTGGCTTGAAGCATTTTATGAGGAAGATAAGCGTCATCGCTTGATTCCTAAAACTAT
AGAGAATGCGCTGTATCGAAAGCTTGAAATCCTAGATGCAGCAAAAGTTGAATCAGATCTAAGAGTTCCACCGGGTAATC
GGTTTGAACATCTTGAAGGCAATCTGAAAGGTTGGTGTTCGATACGGGTGAATAAACAGTATCGTTTGATTTTTAAGTGG
GTTGACGGTGTAGCAGAAGACACCTATTTAGACCCTCATAAGTACTGA

Antitoxin


Download         Length: 126 a.a.        Molecular weight: 14676.60 Da        Isoelectric Point: 6.9354

>AT154350 WP_202170234.1 NZ_CP051507:c958440-958063 [Helicobacter pylori]
MPNSPTKKDCTQYSEKQLFNLINQLERKIKKMQNDRASFKEKMAKELEKRDQNFKDKIDALNELLQKISQVFDDKRDCCL
GHETPNIRTQEAMRDALNKETDLIVEDFSSYSDERKKALGVETQS

Download         Length: 378 bp

>AT154350 NZ_CP068023:c2194723-2194406 [Pseudoalteromonas sp. GCY]
ATGCGCAGAACTAAACGTCGTCCAGTTGGTGTAGGAGAAATGCTCAAAGTTGAATTCTTGGAGCCAATGGAGATTACATC
AAAAACATTAGCAGAAGCTATGGGTGTACATAGGAACACCATCAGTAACTTAATTAATGGTGGTACTCTGACTGCTCCAC
TTGCAATCAAGTTAGCGGCTGCACTTGGGAATACACCTGAGTTTTGGCTTAACATTCAACATGCTGTGGACTTGTGGGAT
ACACGAAATCGTTATCAAGATGAAGCCAAGCAAGTAAAACCTTTGTTTTCAACGCAAGATATCAAACTACGTACATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References