154343

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 932564..933188 Replicon chromosome
Accession NZ_CP051503
Organism Helicobacter pylori strain SHIM-014

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HG564_RS04380 Protein ID WP_000945228.1
Coordinates 932564..932830 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HG564_RS04385 Protein ID WP_202171641.1
Coordinates 932811..933188 (-) Length 126 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HG564_RS04360 929222..929989 - 768 WP_000242371.1 ABC transporter ATP-binding protein -
HG564_RS04365 929989..930969 - 981 WP_000921444.1 iron ABC transporter permease -
HG564_RS04370 930962..931810 - 849 WP_000504112.1 SDR family oxidoreductase -
HG564_RS04375 931954..932478 + 525 WP_001120217.1 acyl-CoA thioesterase -
HG564_RS04380 932564..932830 - 267 WP_000945228.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
HG564_RS04385 932811..933188 - 378 WP_202171641.1 hypothetical protein Antitoxin
HG564_RS04390 933493..935745 - 2253 WP_202171642.1 outer membrane beta-barrel protein -
HG564_RS04405 936080..936708 + 629 Protein_860 hypothetical protein -
HG564_RS04410 936659..937771 - 1113 WP_202171643.1 hydrogenase formation protein HypD -
HG564_RS04415 937774..938010 - 237 WP_000335458.1 HypC/HybG/HupF family hydrogenase formation chaperone -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-87)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10388.24 Da        Isoelectric Point: 9.9832

>T154343 WP_000945228.1 NZ_CP051503:c932830-932564 [Helicobacter pylori]
VLRLNLKKSFQKDFDKLLLNGFDDSVLNKVILSLRKKEPLDPQFQDHALKGKWKPFRECHIKADILLVYLVKDDELILLR
LGSHSERF

Download         Length: 267 bp

>T154343 NZ_CP068018:c4476021-4475653 [Salmonella enterica]
ATGACCCTACAACTTATCTCAGCGGAAGAGATAATTCAGTTTCACGACAGGCTTCTCCGCGTTACGCCTGGTGTAACAGG
CATGCCTGATCCTGGCCGCGCGGAAGCGCTAATGTACCGGGTACTCAAGCAAATCGAATATGAAGGGGTGACCGACGTGT
GGCTGCTGGCGGCAATGCATTTGCTCGCTATATCCCGTGGGCATATCTTCAATGATGGTAACAAACGTACCGCCTTATTT
ATTACGCTGCTGTTTTTAAAGCGTAACGGGATCTCACTCGCTGCGAATCCGGATTTTGTCGATATGACAGTCGATGCGGC
GGCAGGGCGGCTTACGCTGGAGCAAATTGCCGTTCGCTTACGTGCCTGA

Antitoxin


Download         Length: 126 a.a.        Molecular weight: 14658.62 Da        Isoelectric Point: 7.7122

>AT154343 WP_202171641.1 NZ_CP051503:c933188-932811 [Helicobacter pylori]
MPNSPTKKDCTQYSEKQLFNLINQLERKIKKMQNDRVSFKEKMAKELEKRDQNFKDKIDALNELLQKISQAFNNKRDCCL
GHEIPNLETQQAMRDALNKETDLIVEDFSSYSDERKKALGVETQS

Download         Length: 378 bp

>AT154343 NZ_CP068018:c4476239-4476018 [Salmonella enterica]
ATGCGTACGGTTAACTATAGCGAAGCGCGGCAAAATCTGGCCGAAGTCCTGGAAAGTGCGGTGACGGGGGGGCCTGTTAC
CATCACGCGTCGTGGGCATAAGTCCGCAGTGATCATCAGCGCCGAGGAGTTTGAGCGTTATCAGACGGCGCGAATGGATG
ATGAGTTTGCTGCCATTATGGCGGTTCATGGCAATGAGCTCAGGGAGCTGGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References