Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 933979..934597 Replicon chromosome
Accession NZ_CP051500
Organism Helicobacter pylori strain PUNO-003

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HG567_RS04345 Protein ID WP_202163673.1
Coordinates 933979..934239 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HG567_RS04350 Protein ID WP_202163674.1
Coordinates 934226..934597 (-) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HG567_RS04315 929964..930731 - 768 WP_000242349.1 ABC transporter ATP-binding protein -
HG567_RS04320 930731..931711 - 981 WP_000921461.1 iron ABC transporter permease -
HG567_RS04325 931704..932567 - 864 WP_202163671.1 SDR family oxidoreductase -
HG567_RS04330 932707..933231 + 525 WP_001135623.1 acyl-CoA thioesterase -
HG567_RS04335 933336..933603 - 268 Protein_849 type II toxin-antitoxin system YafQ family toxin -
HG567_RS04340 933590..933901 - 312 WP_202163672.1 hypothetical protein -
HG567_RS04345 933979..934239 - 261 WP_202163673.1 type II toxin-antitoxin system YafQ family toxin Toxin
HG567_RS04350 934226..934597 - 372 WP_202163674.1 hypothetical protein Antitoxin
HG567_RS04355 935088..937313 - 2226 WP_202163675.1 outer membrane beta-barrel protein -
HG567_RS04370 937668..938294 + 627 WP_202139321.1 hypothetical protein -
HG567_RS04375 938245..939357 - 1113 WP_202163676.1 hydrogenase formation protein HypD -
HG567_RS04380 939363..939596 - 234 WP_202139323.1 HypC/HybG/HupF family hydrogenase formation chaperone -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10313.19 Da        Isoelectric Point: 9.6561

>T154339 WP_202163673.1 NZ_CP051500:c934239-933979 [Helicobacter pylori]
MLKIRHHIFFKKDFKKLVKNGFDDSVLNEVILRKKEPLDPRFQDHALKGKWKPFRECHIKADILLVYLVEDDELILLRLG
SHSELF

Download         Length: 261 bp

>T154339 NZ_CP068018:3715456-3715983 [Salmonella enterica]
ATGATGTTTACAGACTGGCATGAGGCCGCGATAGGGAAAACCCACAATCGAATGAATTTTGATTGTGGGGATGCCGATCT
GAACCAATTCCTGCAACGCCATGCACGACAAAATCATGAGAAAGGGACAACGAAAACCTATGTTGCGCTTGATAATTCGG
ATGTTACACGTATCCACGGCTTTTACTCAGTCAGTCCTGCATCACTGATATATGCACAGGTTCCCGGCGCAATCAGCAAA
GGATTAGGGAGATACGATGTGCCGGTGTTTCGTCTGGGTCGTTTAGCCGTAGACAAATCTATGCAGGGGCAAGGGCTGGG
AGCACAACTTTTGTTATCTGCCGGAAAGCGTTGCATACAGGCGGCTTTGCAGGTCGGTGGCGTAGCCCTACTTATTGATG
CCAAAAATAAACAGGTCTGCGACTGGTACAAAGGATTTGGCGCAGTACCATTAAACGATCAACCCCTTTCCTTGTTGCTG
TCGTTTAAAACGCTTTATGCTGCTTTATCTGCATCTGGTAGGTTATGA

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 14553.43 Da        Isoelectric Point: 5.8373

>AT154339 WP_202163674.1 NZ_CP051500:c934597-934226 [Helicobacter pylori]
MPNTTAKKDYTKYSEKQLFNLIHQLERKIKKMQNDRVSFKEKMAKELEKRDQNFKDKIDALNELLQKISQAFDDKRDCCL
GHETPNIETQQAMRDALKDENLETIEDFSAWANEVKKEVNAEN

Download         Length: 372 bp

>AT154339 NZ_CP068018:3715169-3715459 [Salmonella enterica]
ATGAAAACCATGCCTCAGATAGCTATAGAATCTAACGAAAGGCTGTCGTTACGTGTATCGACGGATGCCAAAAAGTTGAT
AGTCCGCGCTGCGGCAATCCAGCAAACCAACCTGACGGATTTTGTGGTCAGTAACATACTACCTGTCGCACAGAAGATTG
TTGATGCCGCCGAACGGGTATATCTGACGGAGCGCGATACTAAAATGATCATGGAAATTTTAGATAACCCGCCAGCGCCG
AATGAAAAGCTTCTTGCCGCTGCTTTCGCCCTGCCGGACATGAAGAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References