Detailed information of TA system TA154338

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafQ(toxin)
• Location: 933590..934239
• Replicon: chromosome
• Accession: NZ_CP051500
• Organism: Helicobacter pylori strain PUNO-003

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HG567_RS04345
• Protein ID: WP_202163673.1
• Coordinates: 933979..934239 (-)
• Length: 87 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: HG567_RS04340
• Protein ID: WP_202163672.1
• Coordinates: 933590..933901 (-)
• Length: 104 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HG567_RS04315	929964..930731	-	768	WP_000242349.1	ABC transporter ATP-binding protein	-
HG567_RS04320	930731..931711	-	981	WP_000921461.1	iron ABC transporter permease	-
HG567_RS04325	931704..932567	-	864	WP_202163671.1	SDR family oxidoreductase	-
HG567_RS04330	932707..933231	+	525	WP_001135623.1	acyl-CoA thioesterase	-
HG567_RS04335	933336..933603	-	268	Protein_849	type II toxin-antitoxin system YafQ family toxin	-
HG567_RS04340	933590..933901	-	312	WP_202163672.1	hypothetical protein	Antitoxin
HG567_RS04345	933979..934239	-	261	WP_202163673.1	type II toxin-antitoxin system YafQ family toxin	Toxin
HG567_RS04350	934226..934597	-	372	WP_202163674.1	hypothetical protein	-
HG567_RS04355	935088..937313	-	2226	WP_202163675.1	outer membrane beta-barrel protein	-
HG567_RS04370	937668..938294	+	627	WP_202139321.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (3-86)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 87 a.a.
• Molecular weight: 10313.19 Da
• Isoelectric Point: 9.6561

>T154338 WP_202163673.1 NZ_CP051500:c934239-933979 [Helicobacter pylori]
MLKIRHHIFFKKDFKKLVKNGFDDSVLNEVILRKKEPLDPRFQDHALKGKWKPFRECHIKADILLVYLVEDDELILLRLG
SHSELF

Nucleotide

• Length: 261 bp

>T154338 NZ_CP068018:c2634842-2634739 [Salmonella enterica]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin

Protein

• Length: 104 a.a.
• Molecular weight: 12349.22 Da
• Isoelectric Point: 10.0373

>AT154338 WP_202163672.1 NZ_CP051500:c933901-933590 [Helicobacter pylori]
MPNTTAEKDYTKYSEKQLFNFLNSIKTKQKRALEKLKEIQAQKQRIKKALQFKVLHLTENGYTIEEEREILVRAKDTKNH
LCFKSIEDFKKHCENLRFKNADD

Nucleotide

• Length: 312 bp

>AT154338 NZ_CP068018:2634737-2634882 [Salmonella enterica]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG