154336

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 889649..890291 Replicon chromosome
Accession NZ_CP051499
Organism Helicobacter pylori strain PUNO-004

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HG568_RS04205 Protein ID WP_202167164.1
Coordinates 889649..889924 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HG568_RS04210 Protein ID WP_202167165.1
Coordinates 889905..890291 (-) Length 129 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HG568_RS04185 886310..887077 - 768 WP_202167162.1 ABC transporter ATP-binding protein -
HG568_RS04190 887077..888057 - 981 WP_000921450.1 iron ABC transporter permease -
HG568_RS04195 888050..888892 - 843 WP_202167163.1 SDR family oxidoreductase -
HG568_RS04200 889032..889556 + 525 WP_001135623.1 acyl-CoA thioesterase -
HG568_RS04205 889649..889924 - 276 WP_202167164.1 YafQ family addiction module toxin Toxin
HG568_RS04210 889905..890291 - 387 WP_202167165.1 hypothetical protein Antitoxin
HG568_RS04215 890544..892772 - 2229 WP_202167166.1 outer membrane beta-barrel protein -
HG568_RS04230 893086..893723 + 638 Protein_826 hypothetical protein -
HG568_RS04235 893674..894786 - 1113 WP_202167167.1 hydrogenase formation protein HypD -
HG568_RS04240 894789..895025 - 237 WP_202167168.1 HypC/HybG/HupF family hydrogenase formation chaperone -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-85)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10722.47 Da        Isoelectric Point: 8.6277

>T154336 WP_202167164.1 NZ_CP051499:c889924-889649 [Helicobacter pylori]
VLKLNLKKSFQKDFDKLLLNGFDDSVLNEVILRKKEPLDPQFQDHALKGNWKPFRERHIKADILLVYLVKDDELILLRLG
SHSELNHPHNL

Download         Length: 276 bp

>T154336 NZ_CP068018:c1241776-1241558 [Salmonella enterica]
ATGTCTGATAAACCATTAACTAAAACTGATTATTTGATGCGTTTACGGCGCTGTCAGACAATTGACACTCTGGAGCGCGT
CATTGAGAAAAATAAATATGAATTGTCCGACAATGAGCTGGCTGTATTTTACTCAGCTGCGGATCACCGTCTTGCAGAAT
TGACGATGAACAAACTCTACGACAAGATCCCCTCTTCAGTATGGAAATTCATTCGTTAA

Antitoxin


Download         Length: 129 a.a.        Molecular weight: 14917.88 Da        Isoelectric Point: 5.9695

>AT154336 WP_202167165.1 NZ_CP051499:c890291-889905 [Helicobacter pylori]
MPNSPTKKDCTRYSEKQLFSLINQLEQKIKKMQNDRVSFKEKMAKELEKRDQNFKDKIDALNELLQKISQAFDDKRDCCL
GHEIPNLETQQAMRDALNGENLETDLIVEDFSSYSDERKKALGVKTQS

Download         Length: 387 bp

>AT154336 NZ_CP068018:c1242178-1241804 [Salmonella enterica]
ATGGACGAATACTCACCCAAAAGACATGATATAGCACAGCTTAAATTTCTTTGCGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAAGAAAGCAACCATGGCTGGGTTAATGACCCGACCTCAGCAGTCAACCTGCAGCTCAATGAGCTGATAGAGC
ATATTGCAACTTTCGCGCTTAATTATAAAATTAAGTACAATGAAGACAATAAATTGATTGCGCAGATAGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGCTATGGTATTAATACGCAGGATTTGCAAAAATGGCGTAAATCGGGCAACCGCCT
GTTCCGTTGTTTCGTCAACGCCACCAGGGCCAATCCTGTTAGTTTGTCTTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References