Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 936793..937363 Replicon chromosome
Accession NZ_CP051494
Organism Helicobacter pylori strain PUNO-010

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HG573_RS04370 Protein ID WP_202146932.1
Coordinates 936793..937065 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HG573_RS04375 Protein ID WP_202146933.1
Coordinates 937052..937363 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HG573_RS04345 932235..933357 - 1123 Protein_851 glycosyltransferase family 8 protein -
HG573_RS04350 933421..934188 - 768 WP_000242345.1 ABC transporter ATP-binding protein -
HG573_RS04355 934188..935168 - 981 WP_000921441.1 iron ABC transporter permease -
HG573_RS04360 935161..936024 - 864 WP_202146931.1 SDR family oxidoreductase -
HG573_RS04365 936164..936688 + 525 WP_097684008.1 acyl-CoA thioesterase -
HG573_RS04370 936793..937065 - 273 WP_202146932.1 type II toxin-antitoxin system YafQ family toxin Toxin
HG573_RS04375 937052..937363 - 312 WP_202146933.1 hypothetical protein Antitoxin
HG573_RS04380 937599..939812 - 2214 WP_202146934.1 outer membrane beta-barrel protein -
HG573_RS04395 940626..940891 - 266 Protein_859 hypothetical protein -
HG573_RS04400 940858..941970 - 1113 WP_202146935.1 hydrogenase formation protein HypD -
HG573_RS04405 941989..942225 - 237 WP_000335458.1 HypC/HybG/HupF family hydrogenase formation chaperone -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10599.61 Da        Isoelectric Point: 9.7265

>T154330 WP_202146932.1 NZ_CP051494:c937065-936793 [Helicobacter pylori]
MLMIETSKKFDKDLKILVKNGFDLKLLYKVVENLAKEQPLDPKYKDHPLKGALKDFRECHLKPDLLLVYQVKKQENTLFL
LRLGSHSELF

Download         Length: 273 bp

>T154330 NZ_CP068015:c5520137-5519754 [Klebsiella pneumoniae]
ATGACCTCCGGATCTGCGCTTTTTGATACCAATATTCTTATTGATTTATTTAGCGGGCGTTGCGAAGCCAAACAGGCGCT
GGAGGCCTGGCCACCGCAGAATGCGATCAGTCTGATTACCTGGATGGAGGTGATGGTTGGCGCTAAAAAATATCACCAGG
AGCAGCGCACGCGAATGGCGCTGAGCACCTTTAATATCATTAACATCTCACAGGATATTGCAGAGCGAAGCGTTGCGCTG
CGGCAGGAGTATAAGCTTAAGCTGCCGGATGCCATCATTCTGGCGACGGCGCAACTCCATCGTCTGGAACTAATTACGCG
GAATACGAAGGGTTTTGCCGGTATTCCTGGCGTAGTCACGCCGTACGAAATCCACCCTGAATAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 12270.12 Da        Isoelectric Point: 10.1678

>AT154330 WP_202146933.1 NZ_CP051494:c937363-937052 [Helicobacter pylori]
MPNSPTKKDYTQYSEKQLFNFLNSIKTKQKRALEKLKEIQVQKQRIKKALQVKALHLTENGYTIEEEREILARAKDTKNH
LCFKSVEDFKKHCENLRFKNADD

Download         Length: 312 bp

>AT154330 NZ_CP068015:c5520379-5520137 [Klebsiella pneumoniae]
ATGATGGCTGAAAGGGATATGGGCAGAATTCTTCTCGATTTATCAGACGATGTCATTCAACGTCTCGATGACCTCAAAGT
GCAGCGTAACATTCCGCGAGCGGAACTGTTACGTGAAGCGGTTGAACAATATCTGGAGAAACAAGATCGAGCTAAAGATA
CCATCTCCAGTGCGCTGGGTCTGTGGCAAGACTGCGAAGAAGACGGCATGGAATATCAACGTCAGCTACGCAAGGAGTGG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References