Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4000540..4000685 Replicon chromosome
Accession NZ_CP051490
Organism Klebsiella pneumoniae strain M297-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4000547..4000649 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4000540..4000685 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HGK25_RS19440 (HGK25_19815) 3996072..3997505 + 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
HGK25_RS19445 (HGK25_19820) 3997621..3997860 + 240 WP_002911393.1 YebV family protein -
HGK25_RS19450 (HGK25_19825) 3997958..3998149 + 192 WP_002911395.1 YebW family protein -
HGK25_RS19455 (HGK25_19830) 3998146..3998799 - 654 WP_014343242.1 protein-serine/threonine phosphatase -
HGK25_RS19460 (HGK25_19835) 3998956..3999924 + 969 WP_004151446.1 VirK/YbjX family protein -
HGK25_RS19465 (HGK25_19840) 4000029..4000172 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4000540..4000685 + 146 - - Antitoxin
- 4000547..4000649 - 103 - - Toxin
HGK25_RS19470 (HGK25_19845) 4000808..4001146 - 339 WP_065888598.1 YebY family protein -
HGK25_RS19475 (HGK25_19850) 4001163..4002032 - 870 WP_065888599.1 copper homeostasis membrane protein CopD -
HGK25_RS19480 (HGK25_19855) 4002036..4002410 - 375 WP_016529032.1 CopC domain-containing protein YobA -
HGK25_RS19485 (HGK25_19860) 4002523..4002753 + 231 WP_002911406.1 DNA polymerase III subunit theta -
HGK25_RS19490 (HGK25_19865) 4002832..4003491 + 660 WP_004145547.1 exodeoxyribonuclease X -
HGK25_RS19495 (HGK25_19870) 4003495..4005555 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T154315 NZ_CP051490:c4000649-4000547 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT154315 NZ_CP051490:4000540-4000685 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References