Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | TsaAT/- |
Location | 1206612..1207089 | Replicon | chromosome |
Accession | NZ_CP051482 | ||
Organism | Staphylococcus aureus strain NGA104a |
Toxin (Protein)
Gene name | TsaT | Uniprot ID | T1Y7S2 |
Locus tag | HGO93_RS06080 | Protein ID | WP_000052076.1 |
Coordinates | 1206901..1207089 (+) | Length | 63 a.a. |
Antitoxin (Protein)
Gene name | TsaA | Uniprot ID | T1Y6P8 |
Locus tag | HGO93_RS06075 | Protein ID | WP_001059690.1 |
Coordinates | 1206612..1206872 (+) | Length | 87 a.a. |
Genomic Context
Location: 1202871..1203293 (423 bp)
Type: Others
Protein ID: WP_000974460.1
Type: Others
Protein ID: WP_000974460.1
Location: 1203692..1204186 (495 bp)
Type: Others
Protein ID: WP_000569884.1
Type: Others
Protein ID: WP_000569884.1
Location: 1204341..1204958 (618 bp)
Type: Others
Protein ID: Protein_1167
Type: Others
Protein ID: Protein_1167
Location: 1205836..1206072 (237 bp)
Type: Others
Protein ID: WP_000368687.1
Type: Others
Protein ID: WP_000368687.1
Location: 1206612..1206872 (261 bp)
Type: Antitoxin
Protein ID: WP_001059690.1
Type: Antitoxin
Protein ID: WP_001059690.1
Location: 1206901..1207089 (189 bp)
Type: Toxin
Protein ID: WP_000052076.1
Type: Toxin
Protein ID: WP_000052076.1
Location: 1207277..1207846 (570 bp)
Type: Others
Protein ID: WP_001106654.1
Type: Others
Protein ID: WP_001106654.1
Location: 1207934..1208218 (285 bp)
Type: Others
Protein ID: WP_001004401.1
Type: Others
Protein ID: WP_001004401.1
Location: 1208280..1208498 (219 bp)
Type: Others
Protein ID: WP_000005886.1
Type: Others
Protein ID: WP_000005886.1
Location: 1202007..1202723 (717 bp)
Type: Others
Protein ID: WP_000150012.1
Type: Others
Protein ID: WP_000150012.1
Location: 1205031..1205612 (582 bp)
Type: Others
Protein ID: WP_001140696.1
Type: Others
Protein ID: WP_001140696.1
Location: 1206069..1206272 (204 bp)
Type: Others
Protein ID: WP_000145163.1
Type: Others
Protein ID: WP_000145163.1
Location: 1208994..1209194 (201 bp)
Type: Others
Protein ID: WP_001059082.1
Type: Others
Protein ID: WP_001059082.1
Location: 1209551..1210237 (687 bp)
Type: Others
Protein ID: WP_001793574.1
Type: Others
Protein ID: WP_001793574.1
Location: 1210578..1211099 (522 bp)
Type: Others
Protein ID: WP_000824464.1
Type: Others
Protein ID: WP_000824464.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HGO93_RS06040 (1202007) | 1202007..1202723 | - | 717 | WP_000150012.1 | type I 3-dehydroquinate dehydratase | - |
HGO93_RS06045 (1202871) | 1202871..1203293 | + | 423 | WP_000974460.1 | organic hydroperoxide resistance protein | - |
HGO93_RS06050 (1203692) | 1203692..1204186 | + | 495 | WP_000569884.1 | GNAT family N-acetyltransferase | - |
HGO93_RS06055 (1204341) | 1204341..1204958 | + | 618 | Protein_1167 | LysE/ArgO family amino acid transporter | - |
HGO93_RS06060 (1205031) | 1205031..1205612 | - | 582 | WP_001140696.1 | histidine phosphatase family protein | - |
HGO93_RS06065 (1205836) | 1205836..1206072 | + | 237 | WP_000368687.1 | hypothetical protein | - |
HGO93_RS06070 (1206069) | 1206069..1206272 | - | 204 | WP_000145163.1 | sterile alpha motif-like domain-containing protein | - |
HGO93_RS06075 (1206612) | 1206612..1206872 | + | 261 | WP_001059690.1 | hypothetical protein | Antitoxin |
HGO93_RS06080 (1206901) | 1206901..1207089 | + | 189 | WP_000052076.1 | hypothetical protein | Toxin |
HGO93_RS06085 (1207277) | 1207277..1207846 | + | 570 | WP_001106654.1 | lipoprotein N-acylation protein LnsA | - |
HGO93_RS06090 (1207934) | 1207934..1208218 | + | 285 | WP_001004401.1 | hypothetical protein | - |
HGO93_RS06095 (1208280) | 1208280..1208498 | + | 219 | WP_000005886.1 | hypothetical protein | - |
HGO93_RS06100 (1208994) | 1208994..1209194 | - | 201 | WP_001059082.1 | cold-shock protein | - |
HGO93_RS06105 (1209551) | 1209551..1210237 | - | 687 | WP_001793574.1 | thermonuclease family protein | - |
HGO93_RS06110 (1210578) | 1210578..1211099 | - | 522 | WP_000824464.1 | hypothetical protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | vWbp / clfA | 1205836..1234041 | 28205 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 63 a.a. Molecular weight: 7142.82 Da Isoelectric Point: 9.9971
>T154240 WP_000052076.1 NZ_CP051482:1206901-1207089 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL
Download Length: 189 bp
>T154240 NZ_CP067417:c2117363-2116053 [Aeromonas media]
ATGGCCAGCCTGACGGTCTACATGAACGGATACCGGGTAGGTACCTTTACCAAGGCGACCAATGGTGCTCACCAATTTCA
GTACGATGAATCGTGGGTGAAGTTGCCAGGCAGCCGCCCCATCTCGCTCTCCATGCCATTACGCCAGCAGCGCTACCAGG
GCGATGAGGCCTATAACTTCTTCGATAATCTGCTGCCAGATAACCCGGAAGTAAGAAACCGGGTGGTGGCGCGCTATCAA
GCCGATTCCACCCAACCCTTTGATCTGCTCAGTTGCATTGGCCAGGACAGCGTGGGGGCATTGCAACTGGTGGCTCAGGG
CAGACCTGTGCCAGACGTTAAGCGCATTGAGTGCAAGCCGCTCTCTGACGCCGAACTGGAGCAGATCATGACCAGCTACC
AGCAAGGGATCCCGCTTGGTATGGTGAGGGAAGAGGACGATTTTCGGATATCCATCGCCGGGGCTCAGGAAAAGACCGCG
TTACTCTACCTCGACAACCGTTGGTGCTTACCGCATGCAGCGACCCCAACCACCCACATTATCAAGCTGCCCATTGGCAA
GATCGAAAGCCACTCCTACTCGATAGACCTCTCCCAGAGCGTAGAAAACGAATATCTCTGCACCCTGATCGCCAAAGCAT
TGGGTCTTCCGGTTCCCCATTGCTTCATCATGCAGGTCGGCAAGGTCAAGGCTCTGGCGGTGGAACGCTTCGATCGGCGC
TACGCCACGGATCGCAGTTGGATCATGCGCCTGCCCCAAGAGGACTTCTGCCAGGTGTTGAATGTACCGTCAGCACGCAA
GTACGAGAGCCATGGTGGACCGGGCATTGCTGACATCATGACGACCCTGCTGGGATCGGCCACGCCGGAGCAGGATCGGT
ACCTGTTTATGAAGTCTCAGGTGTTGTTCTGGCTGCTGGCTGCCACTGATGGCCATGCCAAGAATTTCTCGGTGTTTATC
GAACCTGAAGGGCGTTTCCGGCTTACACCGTTTTACGACATCCTTTCCATGTATCCTGCATTTGGTGGTAAAGGATTACA
TCCCCGTGATGCCAAGTTGGCCATGGGGCTTACTGCAACCAAGGGCAAAAAATACGCGATAGAGCAGATATTTCCTCGCC
ATTTTTATCAAACGGCCAAGGCGATTGGTTTTGAACAAGTGCAGATGGAAAAAATCATCAGCGAACTGACGGATAATCTG
GATGAGGTAATATCAATCGTTCGTCAGCAATTGCCTGATACATTTCCCACTGAGATTGCAGATTCAATTTTGGGTGGACT
CAGTTCGAAAGCGCAACGCTTAAAACGATAA
ATGGCCAGCCTGACGGTCTACATGAACGGATACCGGGTAGGTACCTTTACCAAGGCGACCAATGGTGCTCACCAATTTCA
GTACGATGAATCGTGGGTGAAGTTGCCAGGCAGCCGCCCCATCTCGCTCTCCATGCCATTACGCCAGCAGCGCTACCAGG
GCGATGAGGCCTATAACTTCTTCGATAATCTGCTGCCAGATAACCCGGAAGTAAGAAACCGGGTGGTGGCGCGCTATCAA
GCCGATTCCACCCAACCCTTTGATCTGCTCAGTTGCATTGGCCAGGACAGCGTGGGGGCATTGCAACTGGTGGCTCAGGG
CAGACCTGTGCCAGACGTTAAGCGCATTGAGTGCAAGCCGCTCTCTGACGCCGAACTGGAGCAGATCATGACCAGCTACC
AGCAAGGGATCCCGCTTGGTATGGTGAGGGAAGAGGACGATTTTCGGATATCCATCGCCGGGGCTCAGGAAAAGACCGCG
TTACTCTACCTCGACAACCGTTGGTGCTTACCGCATGCAGCGACCCCAACCACCCACATTATCAAGCTGCCCATTGGCAA
GATCGAAAGCCACTCCTACTCGATAGACCTCTCCCAGAGCGTAGAAAACGAATATCTCTGCACCCTGATCGCCAAAGCAT
TGGGTCTTCCGGTTCCCCATTGCTTCATCATGCAGGTCGGCAAGGTCAAGGCTCTGGCGGTGGAACGCTTCGATCGGCGC
TACGCCACGGATCGCAGTTGGATCATGCGCCTGCCCCAAGAGGACTTCTGCCAGGTGTTGAATGTACCGTCAGCACGCAA
GTACGAGAGCCATGGTGGACCGGGCATTGCTGACATCATGACGACCCTGCTGGGATCGGCCACGCCGGAGCAGGATCGGT
ACCTGTTTATGAAGTCTCAGGTGTTGTTCTGGCTGCTGGCTGCCACTGATGGCCATGCCAAGAATTTCTCGGTGTTTATC
GAACCTGAAGGGCGTTTCCGGCTTACACCGTTTTACGACATCCTTTCCATGTATCCTGCATTTGGTGGTAAAGGATTACA
TCCCCGTGATGCCAAGTTGGCCATGGGGCTTACTGCAACCAAGGGCAAAAAATACGCGATAGAGCAGATATTTCCTCGCC
ATTTTTATCAAACGGCCAAGGCGATTGGTTTTGAACAAGTGCAGATGGAAAAAATCATCAGCGAACTGACGGATAATCTG
GATGAGGTAATATCAATCGTTCGTCAGCAATTGCCTGATACATTTCCCACTGAGATTGCAGATTCAATTTTGGGTGGACT
CAGTTCGAAAGCGCAACGCTTAAAACGATAA
Antitoxin
Download Length: 87 a.a. Molecular weight: 9940.09 Da Isoelectric Point: 4.0624
>AT154240 WP_001059690.1 NZ_CP051482:1206612-1206872 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG
Download Length: 261 bp
>AT154240 NZ_CP067417:c2117617-2117363 [Aeromonas media]
ATGAAAGTAACCAGCGCCAAGCAACTTAGTGCCTGTCTCAAGGATGCCAGGCTTTCGCAAAAGCTCTCCCAAGGCAAAGT
GGCCGGCAAGGTGGGGATCAGGCAGGACACGGTGTCCAGCTTCGAGCTCAATCCCGAGTCAACCAAGCTGGAGACCTTGT
TCAAGATCCTCGCCGCACTGGAACTCTCCCTCGATATCAGGCCCCGCACCGATCCTGCGGAAAACGCCACGCCTGGCTGG
AAGGAGGAGTGGTAA
ATGAAAGTAACCAGCGCCAAGCAACTTAGTGCCTGTCTCAAGGATGCCAGGCTTTCGCAAAAGCTCTCCCAAGGCAAAGT
GGCCGGCAAGGTGGGGATCAGGCAGGACACGGTGTCCAGCTTCGAGCTCAATCCCGAGTCAACCAAGCTGGAGACCTTGT
TCAAGATCCTCGCCGCACTGGAACTCTCCCTCGATATCAGGCCCCGCACCGATCCTGCGGAAAACGCCACGCCTGGCTGG
AAGGAGGAGTGGTAA
Structures
Toxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0E0VP18 |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0E0VN56 |