Detailed information of TA system TA154215

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 447944..448585
• Replicon: chromosome
• Accession: NZ_CP051474
• Organism: Acinetobacter baumannii strain VB2107

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: HBN37_RS02180
• Protein ID: WP_000607077.1
• Coordinates: 448196..448585 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: HBN37_RS02175
• Protein ID: WP_011860336.1
• Coordinates: 447944..448189 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HBN37_RS02155	443448..444455	+	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-
HBN37_RS02160	444474..444851	+	378	WP_001216380.1	50S ribosomal protein L17	-
HBN37_RS02165	445033..446523	+	1491	WP_000415125.1	NAD(P)/FAD-dependent oxidoreductase	-
HBN37_RS02170	446572..447744	-	1173	WP_001190542.1	acyl-CoA dehydrogenase family protein	-
HBN37_RS02175	447944..448189	+	246	WP_011860336.1	succinate dehydrogenase assembly factor 2	Antitoxin
HBN37_RS02180	448196..448585	+	390	WP_000607077.1	membrane protein	Toxin
HBN37_RS02185	449355..450440	+	1086	WP_000049106.1	hypothetical protein	-
HBN37_RS02190	450518..451084	+	567	WP_000651538.1	rhombosortase	-
HBN37_RS02195	451272..453467	+	2196	WP_001158906.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (6-78)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15552.88 Da
• Isoelectric Point: 10.4313

>T154215 WP_000607077.1 NZ_CP051474:448196-448585 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T154215 NZ_CP067399:3747199-3747477 [Escherichia coli]
ATGATTCAAAGGGATATTGAATACTCGGGACAATATTCAAAGGATGTAAAACTTGCACAAAAGCGTCATAAGGATATGAA
TAAATTGAAATATCTTATGACGCTTCTTATCAATAATACTTTACCGCTTCCAGCTGTTTATAAAGACCACCCGCTGCAAG
GTTCATGGAAAGGTTATCGCGATGCTCATGTCGAACCGGACTGGATCCTGATTTACAAACTTACCGATAAACTTTTACGA
TTTGAGAGAACTGGAACTCACGCGGCGCTCTTTGGGTAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9842.27 Da
• Isoelectric Point: 4.9001

>AT154215 WP_011860336.1 NZ_CP051474:447944-448189 [Acinetobacter baumannii]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLKHYVH
G

Nucleotide

• Length: 246 bp

>AT154215 NZ_CP067399:3746936-3747196 [Escherichia coli]
ATGGCTGCTAACGCGTTTGTTCGCGCCCGAATCGATGAAGATCTGAAGAATCAGGCAGCGGACGTACTGGCCGGGATGGG
GCTGACCATCTCTGACCTGGTTCGCATAACCCTCACAAAGGTCGCGCGTGAAAAGGCATTGCCGTTTGATTTACGCGAGC
CTAATCAATTAACCATTCAATCAATCAAAAACAGCGAAGCTGGCATTGATGTTCATAAGGCCAAAGACGCCGATGATTTA
TTTGATAAATTAGGAATTTAA