Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 76344..76915 Replicon chromosome
Accession NZ_CP051461
Organism Polaromonas vacuolata strain KCTC 22033

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag HC248_RS00345 Protein ID WP_168920745.1
Coordinates 76547..76915 (+) Length 123 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag HC248_RS00340 Protein ID WP_168920744.1
Coordinates 76344..76550 (+) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HC248_RS00325 74295..74972 + 678 WP_168920741.1 nitroreductase family protein -
HC248_RS00330 75696..75908 + 213 WP_168920742.1 hypothetical protein -
HC248_RS00335 75947..76174 + 228 WP_168920743.1 hypothetical protein -
HC248_RS00340 76344..76550 + 207 WP_168920744.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
HC248_RS00345 76547..76915 + 369 WP_168920745.1 VapC toxin family PIN domain ribonuclease Toxin
HC248_RS00350 77239..78198 + 960 WP_168920746.1 chromate resistance protein -
HC248_RS00355 78488..79405 + 918 WP_168920747.1 superoxide dismutase -
HC248_RS00360 79680..80393 - 714 WP_168920748.1 anti-sigma factor -
HC248_RS00365 80390..80968 - 579 WP_202882440.1 sigma-70 family RNA polymerase sigma factor -
HC248_RS00370 80995..81531 - 537 WP_168920750.1 DUF3455 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(14-57)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13746.06 Da        Isoelectric Point: 5.5543

>T154180 WP_168920745.1 NZ_CP051461:76547-76915 [Polaromonas vacuolata]
MSVLIDTSVWIDYFRHGNDALVTLIEQDFALIHPMVILEIACGTPPAPRLKTLRNLGFLEFCNQASMREVTTFIEHEKLY
GLGCGLVDMTLLASTLITPDTELWTLDKRLADLAKRFGVAHR

Download         Length: 369 bp

>T154180 NZ_CP051461:76547-76915 [Polaromonas vacuolata]
ATGAGCGTGCTCATTGATACATCGGTATGGATAGACTATTTTCGACATGGAAACGATGCGTTGGTCACTTTAATCGAACA
AGACTTTGCGCTAATCCACCCCATGGTCATACTCGAAATTGCCTGTGGTACGCCCCCTGCGCCACGCTTAAAGACTTTAA
GAAATCTTGGCTTTTTAGAATTCTGTAATCAGGCAAGCATGCGTGAGGTGACGACTTTTATTGAGCACGAAAAGTTGTAT
GGGCTTGGGTGTGGGTTGGTGGATATGACGTTGCTGGCATCCACACTTATTACGCCAGATACTGAGCTGTGGACGCTCGA
TAAGCGCCTTGCAGATTTGGCCAAACGTTTTGGCGTAGCGCATCGTTAG

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7576.73 Da        Isoelectric Point: 5.0323

>AT154180 WP_168920744.1 NZ_CP051461:76344-76550 [Polaromonas vacuolata]
MRTTVTIDDVLYEKALEVADTDMDKADLFREAIKIFVRVKAGKRLAALGGTMPDIQDVPRRAQEPASQ

Download         Length: 207 bp

>AT154180 NZ_CP051461:76344-76550 [Polaromonas vacuolata]
ATGCGCACCACAGTCACTATCGACGATGTTCTTTACGAAAAGGCCCTTGAAGTGGCTGACACCGACATGGATAAAGCAGA
CCTTTTTCGAGAAGCTATCAAAATTTTTGTGCGAGTAAAAGCCGGCAAGCGTCTTGCCGCTTTAGGCGGCACTATGCCGG
ATATTCAAGACGTACCGCGTCGCGCGCAGGAGCCAGCTTCACAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References