Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | DhiAT/dnstrm_HI1420(antitoxin) |
Location | 1684109..1684889 | Replicon | chromosome |
Accession | NZ_CP051460 | ||
Organism | Dickeya solani strain IFB0421 |
Toxin (Protein)
Gene name | dhiT | Uniprot ID | A0A2K8W4P2 |
Locus tag | HAT92_RS07465 | Protein ID | WP_022632927.1 |
Coordinates | 1684109..1684366 (+) | Length | 86 a.a. |
Antitoxin (Protein)
Gene name | dhiA | Uniprot ID | A0A2K8W4X0 |
Locus tag | HAT92_RS07470 | Protein ID | WP_022632928.1 |
Coordinates | 1684374..1684889 (+) | Length | 172 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HAT92_RS07455 | 1680869..1683019 | - | 2151 | WP_022632925.1 | formate dehydrogenase subunit alpha | - |
HAT92_RS07460 | 1683054..1683596 | - | 543 | WP_022632926.1 | 4Fe-4S dicluster domain-containing protein | - |
HAT92_RS07465 | 1684109..1684366 | + | 258 | WP_022632927.1 | DUF4160 domain-containing protein | Toxin |
HAT92_RS07470 | 1684374..1684889 | + | 516 | WP_022632928.1 | DUF2442 domain-containing protein | Antitoxin |
HAT92_RS07475 | 1684968..1685465 | - | 498 | WP_022632929.1 | hydrogenase maturation peptidase HycI | - |
HAT92_RS07480 | 1685458..1685856 | - | 399 | WP_022632930.1 | formate hydrogenlyase maturation HycH family protein | - |
HAT92_RS07485 | 1685853..1686644 | - | 792 | WP_022632931.1 | NADH-quinone oxidoreductase subunit B family protein | - |
HAT92_RS07490 | 1686641..1687210 | - | 570 | WP_022632932.1 | hydrogenase 4 subunit H | - |
HAT92_RS07495 | 1687221..1688948 | - | 1728 | WP_022632933.1 | hydrogenase large subunit | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 10007.56 Da Isoelectric Point: 8.1243
>T154165 WP_022632927.1 NZ_CP051460:1684109-1684366 [Dickeya solani]
MPEVDRLAGLIFHLYFYDDERHYLPHVHVCYGNHELIISIRTGTEIEGYLPNNKRKMALAHIRAHREQLLSMWERAVVGR
NPGKL
MPEVDRLAGLIFHLYFYDDERHYLPHVHVCYGNHELIISIRTGTEIEGYLPNNKRKMALAHIRAHREQLLSMWERAVVGR
NPGKL
Download Length: 258 bp
>T154165 NZ_CP067390:26077-26559 [Klebsiella grimontii]
GTGGGACGTATAACCACGCCCGAGCCGTTATCCAGCTCTCATCAGCTGGCTGAGTTCGTCAGTGGAGAGACAGTCCTCGA
TGAATGGCTAAAACAGAGAGGTTTAAAAAATCAAGCTCTTGGCGCTGCCCGAACGTTCGTTGTTTGCAAGACGGGTACGA
AGCAAGTAGCTGGTTTTTACTCTTTGGCCACCGGTAGCGTTAACCATACGGAAGCGACAGGTAGTCTTCGGCGTAACATG
CCAGATCCTATACCGGTGATTATACTCGCTCGCCTGGCGGTAGATGTCTCATTGCACGGAAAAGGGGTTGGCGCCGATTT
ACTCCACGATGCAGTTCTACGGTGTTATCGCGTAGCTGAGAACATTGGGGTTCGTGCGATAATGGTTCATGCGCTTACTG
AAGAAGCCAAAGGTTTCTATGCTCACCATGGATTTAAGGCATCACAAACTCATGAGAGGACTCTGTTTCTAAAGCTTCCA
TGA
GTGGGACGTATAACCACGCCCGAGCCGTTATCCAGCTCTCATCAGCTGGCTGAGTTCGTCAGTGGAGAGACAGTCCTCGA
TGAATGGCTAAAACAGAGAGGTTTAAAAAATCAAGCTCTTGGCGCTGCCCGAACGTTCGTTGTTTGCAAGACGGGTACGA
AGCAAGTAGCTGGTTTTTACTCTTTGGCCACCGGTAGCGTTAACCATACGGAAGCGACAGGTAGTCTTCGGCGTAACATG
CCAGATCCTATACCGGTGATTATACTCGCTCGCCTGGCGGTAGATGTCTCATTGCACGGAAAAGGGGTTGGCGCCGATTT
ACTCCACGATGCAGTTCTACGGTGTTATCGCGTAGCTGAGAACATTGGGGTTCGTGCGATAATGGTTCATGCGCTTACTG
AAGAAGCCAAAGGTTTCTATGCTCACCATGGATTTAAGGCATCACAAACTCATGAGAGGACTCTGTTTCTAAAGCTTCCA
TGA
Antitoxin
Download Length: 172 a.a. Molecular weight: 19099.82 Da Isoelectric Point: 5.2747
>AT154165 WP_022632928.1 NZ_CP051460:1684374-1684889 [Dickeya solani]
MHKIVEVDVIGDFSLRLTYDDGLVCDINLYQYASSPVFSDVSLFIKFGLLPDGALEWLPDIKISASELRKKGEYVSHTLA
VRERHFADVISRAFYDAVIENRPEILQAALKIAVEKHGNSTVAKEAGAKSRTSLYKSLNKNTHVSLATVVSLAHTVLQLE
ELQLEDLQLEE
MHKIVEVDVIGDFSLRLTYDDGLVCDINLYQYASSPVFSDVSLFIKFGLLPDGALEWLPDIKISASELRKKGEYVSHTLA
VRERHFADVISRAFYDAVIENRPEILQAALKIAVEKHGNSTVAKEAGAKSRTSLYKSLNKNTHVSLATVVSLAHTVLQLE
ELQLEDLQLEE
Download Length: 516 bp
>AT154165 NZ_CP067390:25823-26089 [Klebsiella grimontii]
ATGAAATCAGATGTTCAACTCAACCTAAGAGCTAAAGAGTCTCAGAGAGCACTCATCGATGCTGCTGCAGAGATCCTTCA
TAAATCGCGAACCGACTTTATCCTGGAGATGGCCTGCAAGGCTGCGGAGAATGTGATCCTTGATCGCCGTGTTTTCAATT
TTAACGACGAACAGTATGCAGAGTTCATCGATATGCTCGATGCACCAGTCGAGGATGAGCCCGCCATTAATAAACTACTG
GCAAGGAAACCTCAGTGGGACGTATAA
ATGAAATCAGATGTTCAACTCAACCTAAGAGCTAAAGAGTCTCAGAGAGCACTCATCGATGCTGCTGCAGAGATCCTTCA
TAAATCGCGAACCGACTTTATCCTGGAGATGGCCTGCAAGGCTGCGGAGAATGTGATCCTTGATCGCCGTGTTTTCAATT
TTAACGACGAACAGTATGCAGAGTTCATCGATATGCTCGATGCACCAGTCGAGGATGAGCCCGCCATTAATAAACTACTG
GCAAGGAAACCTCAGTGGGACGTATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2K8W4P2 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2K8W4X0 |