Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 3119547..3120100 Replicon chromosome
Accession NZ_CP051429
Organism Dickeya dianthicola strain 67-19

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag HGI48_RS13950 Protein ID WP_192988884.1
Coordinates 3119547..3119861 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag HGI48_RS13955 Protein ID WP_110372302.1
Coordinates 3119864..3120100 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HGI48_RS13940 3118906..3119280 + 375 Protein_2734 hypothetical protein -
HGI48_RS13945 3119278..3119550 + 273 Protein_2735 molybdopterin-guanine dinucleotide biosynthesis protein MobC -
HGI48_RS13950 3119547..3119861 - 315 WP_192988884.1 CcdB family protein Toxin
HGI48_RS13955 3119864..3120100 - 237 WP_110372302.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
HGI48_RS13960 3120421..3120591 - 171 Protein_2738 DNA primase -
HGI48_RS13965 3120666..3122525 - 1860 WP_192988885.1 hypothetical protein -
HGI48_RS13970 3123167..3123943 - 777 Protein_2740 DUF1738 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11493.40 Da        Isoelectric Point: 7.9859

>T154091 WP_192988884.1 NZ_CP051429:c3119861-3119547 [Dickeya dianthicola]
MQFTVYGNTGKSGVYPLLLDVTSDIIGQLNRRIVIPLLPVEKYPAGRRPERFVPVVRLTDGKEYAVMTHELASIPVQALG
AVFCDASQYRTQVKAAIDFLIDGI

Download         Length: 315 bp

>T154091 NZ_CP067311:3915738-3916073 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCTGG
ACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 9031.05 Da        Isoelectric Point: 6.4792

>AT154091 WP_110372302.1 NZ_CP051429:c3120100-3119864 [Dickeya dianthicola]
MTAKQRNTQSVTMTVERALLVRAREAGINLSATLTTALDAELRHHEAKKWQEENREAIDALNRFHDEHGCFSDEYRTF

Download         Length: 237 bp

>AT154091 NZ_CP067311:3915490-3915738 [Escherichia coli]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References