Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DhiAT/dnstrm_HI1420(antitoxin)
Location 1553132..1553885 Replicon chromosome
Accession NZ_CP051429
Organism Dickeya dianthicola strain 67-19

Toxin (Protein)


Gene name dhiT Uniprot ID -
Locus tag HGI48_RS07290 Protein ID WP_192990817.1
Coordinates 1553132..1553389 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name dhiA Uniprot ID -
Locus tag HGI48_RS07295 Protein ID WP_192990818.1
Coordinates 1553397..1553885 (+) Length 163 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HGI48_RS07275 1548337..1549545 - 1209 WP_192990815.1 putative DNA binding domain-containing protein -
HGI48_RS07280 1549909..1552059 - 2151 WP_192990816.1 formate dehydrogenase subunit alpha -
HGI48_RS07285 1552094..1552636 - 543 WP_022632926.1 4Fe-4S dicluster domain-containing protein -
HGI48_RS07290 1553132..1553389 + 258 WP_192990817.1 DUF4160 domain-containing protein Toxin
HGI48_RS07295 1553397..1553885 + 489 WP_192990818.1 addiction module antitoxin Antitoxin
HGI48_RS07300 1553972..1554469 - 498 WP_192990819.1 hydrogenase maturation peptidase HycI -
HGI48_RS07305 1554462..1554860 - 399 WP_192990820.1 formate hydrogenlyase maturation HycH family protein -
HGI48_RS07310 1554857..1555648 - 792 WP_192990821.1 NADH-quinone oxidoreductase subunit B family protein -
HGI48_RS07315 1555645..1556214 - 570 WP_192990822.1 hydrogenase 4 subunit H -
HGI48_RS07320 1556225..1557952 - 1728 WP_192990823.1 hydrogenase large subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Protein of unknown function DUF4160

(9-74)

Antitoxin

Uncharacterized protein HI1420

(80-157)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10020.63 Da        Isoelectric Point: 9.4806

>T154080 WP_192990817.1 NZ_CP051429:1553132-1553389 [Dickeya dianthicola]
MPEIDRLAGLIFHLYFYDDHRHHLPHIHVCYGNHELIINIRTGTEIEGYLPNNKRKLALAHIRAYRQPLLSMWERAVVGR
NPGKL

Download         Length: 258 bp

>T154080 NZ_CP051429:1553132-1553389 [Dickeya dianthicola]
ATGCCTGAGATCGACAGACTGGCGGGGCTGATTTTCCATTTGTACTTTTATGACGATCATCGGCACCACTTGCCGCATAT
CCATGTCTGCTACGGCAACCATGAACTGATCATCAATATTCGTACCGGAACCGAGATTGAAGGATATCTGCCGAATAACA
AGCGCAAGCTGGCGCTTGCACATATCAGGGCCTATCGGCAACCGTTGCTGAGTATGTGGGAACGGGCGGTAGTGGGGAGA
AATCCGGGAAAACTGTGA

Antitoxin


Download         Length: 163 a.a.        Molecular weight: 18028.63 Da        Isoelectric Point: 7.0619

>AT154080 WP_192990818.1 NZ_CP051429:1553397-1553885 [Dickeya dianthicola]
MHKIVEVDVIGDFSLRLTYEDGLVCDINLYHYAPSPVFSNASQFIKFGLLPDGSLEWLPDIKISASELRKKGEYVSHTLA
VRERNFADVISRAFYDAVIENRPEILQAALKIAVEKHGNSTVAKEAGAKSRTSLYKSLNKNTHVSLATVVSLAHTVLQLE
EK

Download         Length: 489 bp

>AT154080 NZ_CP051429:1553397-1553885 [Dickeya dianthicola]
ATGCATAAAATTGTAGAAGTTGACGTCATTGGCGATTTTTCGTTGCGCCTGACCTATGAAGATGGTCTGGTTTGCGACAT
CAATCTTTATCACTATGCCCCCAGCCCGGTATTTTCGAACGCCAGCCAATTTATCAAGTTTGGGTTGCTGCCGGACGGCT
CGCTGGAATGGCTGCCGGATATTAAGATTTCCGCGTCTGAATTGCGGAAAAAAGGGGAATATGTCAGCCACACGCTGGCG
GTGCGAGAACGGAACTTCGCTGATGTCATCTCTCGCGCTTTCTATGATGCCGTGATTGAAAACCGGCCGGAAATTCTGCA
AGCGGCGTTGAAAATTGCGGTGGAAAAACATGGCAACAGCACGGTGGCGAAAGAGGCGGGGGCGAAAAGCCGCACCAGTC
TGTATAAGTCGCTGAATAAGAATACCCATGTCAGCCTGGCGACGGTGGTCAGCCTGGCGCATACCGTGCTGCAGTTGGAG
GAGAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References