Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 1011204..1011730 Replicon chromosome
Accession NZ_CP051429
Organism Dickeya dianthicola strain 67-19

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag HGI48_RS04820 Protein ID WP_192990507.1
Coordinates 1011204..1011509 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag HGI48_RS04825 Protein ID WP_192990508.1
Coordinates 1011512..1011730 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HGI48_RS04795 1007114..1007863 + 750 WP_192990504.1 hypothetical protein -
HGI48_RS04800 1007853..1009073 + 1221 WP_192990505.1 hypothetical protein -
HGI48_RS04805 1009191..1009758 + 568 Protein_936 transposase -
HGI48_RS04810 1009770..1010543 - 774 WP_192990506.1 transposase -
HGI48_RS04815 1010594..1011100 - 507 Protein_938 transposase -
HGI48_RS04820 1011204..1011509 - 306 WP_192990507.1 type II toxin-antitoxin system toxin CcdB Toxin
HGI48_RS04825 1011512..1011730 - 219 WP_192990508.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
HGI48_RS04830 1011789..1012532 - 744 WP_192990509.1 molybdopterin-guanine dinucleotide biosynthesis protein MobC -
HGI48_RS04835 1013444..1013785 - 342 WP_192990510.1 hypothetical protein -
HGI48_RS04840 1013971..1014165 + 195 WP_192990511.1 DUF3950 domain-containing protein -
HGI48_RS04845 1014094..1014555 - 462 Protein_944 integrase family protein -
HGI48_RS04850 1015358..1016359 + 1002 WP_192990512.1 DUF2971 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 984842..1020927 36085


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-100)

Antitoxin

Post-segregation antitoxin CcdA

(2-72)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11711.54 Da        Isoelectric Point: 4.5355

>T154077 WP_192990507.1 NZ_CP051429:c1011509-1011204 [Dickeya dianthicola]
MQFIVYEYKRASHYKMFVDVQSDIVDTPKRRMVIPLIESHNLSEKVNKTLFPLLRIDGEDYRLMTTELSSVPVEVIGEAI
ADLGEYADEIKDAINLMFWGI

Download         Length: 306 bp

>T154077 NZ_CP067311:641208-642530 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCAAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CTGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCCAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTGACGTTAATACCCGAAGA
CGAAACCGTAACGCATCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGACTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCGCTAGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCACAGGAGAAGACAGCACTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAATGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAATTCCAGGTCTTCCAGTGGTTGATTGGCGCAACGGACGGTCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTTTGGCGACAGCAAAGGTGCTGAGATTCCCGGAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCA
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAAGCAATGTGTT
GAGGTTGCATGGACGGTTAAGCCGAGAATACGGTAGTAAGTGA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8241.22 Da        Isoelectric Point: 7.0126

>AT154077 WP_192990508.1 NZ_CP051429:c1011730-1011512 [Dickeya dianthicola]
MKYRVSVTVDKDNYQVLSAAGINISGLVNDAIGKEARRIKAEEWKKENREGMEEVARFIAQHGSFADENRNW

Download         Length: 219 bp

>AT154077 NZ_CP067311:640942-641208 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTGGCGAATGCAATGAAACTGGTTCGCCAGCAAAATGGCTGGAC
GCAGAGCGAGCTGGCGAAAAAAATTGGTATTAAGCAGGCGACGATTTCCAATTTCGAAAACAACCCTGACAATACCACGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACGCTATGCGACGCGAAAAATGCCTCGCCAGAATCA
ACAGAACAGCAAAATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References