Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | tacAT/ElaA-DUF1778 |
| Location | 30040..30779 | Replicon | plasmid p24355 |
| Accession | NZ_CP051385 | ||
| Organism | Salmonella enterica subsp. enterica serovar Senftenberg strain CVM 24355 | ||
Toxin (Protein)
| Gene name | tacT | Uniprot ID | A0A9E6WPH7 |
| Locus tag | HFS01_RS23795 | Protein ID | WP_013087269.1 |
| Coordinates | 30040..30525 (-) | Length | 162 a.a. |
Antitoxin (Protein)
| Gene name | tacA | Uniprot ID | A0A9E6WPN8 |
| Locus tag | HFS01_RS23800 | Protein ID | WP_007869691.1 |
| Coordinates | 30513..30779 (-) | Length | 89 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HFS01_RS23760 | 25250..25513 | + | 264 | WP_004118209.1 | transposase | - |
| HFS01_RS23765 | 25458..25574 | + | 117 | Protein_30 | transposase domain-containing protein | - |
| HFS01_RS23770 | 25802..26059 | + | 258 | Protein_31 | transposase | - |
| HFS01_RS23775 | 26072..27223 | - | 1152 | WP_001254932.1 | IS30-like element IS30 family transposase | - |
| HFS01_RS23780 | 27288..27884 | + | 597 | Protein_33 | IS3 family transposase | - |
| HFS01_RS23785 | 28166..28393 | + | 228 | Protein_34 | transposase | - |
| HFS01_RS23790 | 28488..29833 | - | 1346 | Protein_35 | ISNCY family transposase | - |
| HFS01_RS23795 | 30040..30525 | - | 486 | WP_013087269.1 | GNAT family N-acetyltransferase | Toxin |
| HFS01_RS23800 | 30513..30779 | - | 267 | WP_007869691.1 | DUF1778 domain-containing protein | Antitoxin |
| HFS01_RS23805 | 31432..31689 | + | 258 | Protein_38 | replication initiation protein | - |
| HFS01_RS23810 | 31723..32157 | - | 435 | WP_000429836.1 | Hg(II)-responsive transcriptional regulator | - |
| HFS01_RS23815 | 32229..32579 | + | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| HFS01_RS23820 | 32593..32868 | + | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| HFS01_RS23825 | 32904..33326 | + | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| HFS01_RS23830 | 33378..35072 | + | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| HFS01_RS23835 | 35090..35452 | + | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| HFS01_RS23840 | 35449..35685 | + | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..111658 | 111658 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 162 a.a. Molecular weight: 23860.62 Da Isoelectric Point: 5.5500
>T154038 WP_013087269.1 NZ_CP051385:c30525-30040 [Salmonella enterica subsp. enterica serovar Senftenberg]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FF
Download Length: 486 bp
>T154038 NZ_CP067303:c3661688-3661392 [Escherichia coli]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCCCTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCCCTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA
Antitoxin
Download Length: 89 a.a. Molecular weight: 13116.73 Da Isoelectric Point: 5.5500
>AT154038 WP_007869691.1 NZ_CP051385:c30779-30513 [Salmonella enterica subsp. enterica serovar Senftenberg]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFF
Download Length: 267 bp
>AT154038 NZ_CP067303:c3661390-3660995 [Escherichia coli]
ATGAAATGTCCGGTTTGCCACCAGGGAGAAATGGTTTCTGGCATTAAAGATATTCCATACACCTTCCGTGGACGAAAAAC
AGTATTGAAAGGTATCCACGGTTTATATTGTGTCCATTGCGAAGAGAGCATCATGAATAAAGAAGAGTCAGATGCTTTCA
TGGCGCAAGTAAAGGCATTTCGGGCTTCGGTGAATGCCGAAACAGTGGCACCTGAATTTATAGTGAAGGTTCGAAAAAAG
CTCTCTCTTACCCAAAAAGAGGCAAGCGAAATTTTTGGGGGAGGTGTAAATGCGTTTTCGCGTTACGAAAAAGGCAATGC
CCAACCTCATCCTTCCACAATCAAACTTTTACGTGTTCTGGATAAGCATCCAGAACTATTGAATGAAATCCGTTAA
ATGAAATGTCCGGTTTGCCACCAGGGAGAAATGGTTTCTGGCATTAAAGATATTCCATACACCTTCCGTGGACGAAAAAC
AGTATTGAAAGGTATCCACGGTTTATATTGTGTCCATTGCGAAGAGAGCATCATGAATAAAGAAGAGTCAGATGCTTTCA
TGGCGCAAGTAAAGGCATTTCGGGCTTCGGTGAATGCCGAAACAGTGGCACCTGAATTTATAGTGAAGGTTCGAAAAAAG
CTCTCTCTTACCCAAAAAGAGGCAAGCGAAATTTTTGGGGGAGGTGTAAATGCGTTTTCGCGTTACGAAAAAGGCAATGC
CCAACCTCATCCTTCCACAATCAAACTTTTACGTGTTCTGGATAAGCATCCAGAACTATTGAATGAAATCCGTTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|