154028

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prpT-prpA/ParE-CC2985
Location 106490..107039 Replicon plasmid p24399
Accession NZ_CP051369
Organism Salmonella enterica subsp. houtenae serovar 43:z4 strain CVM 24399

Toxin (Protein)


Gene name PrpT Uniprot ID -
Locus tag HFS24_RS22965 Protein ID WP_219827449.1
Coordinates 106743..107039 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name PrpA Uniprot ID -
Locus tag HFS24_RS22960 Protein ID WP_258169268.1
Coordinates 106490..106756 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HFS24_RS22935 (HFS24_22880) 101763..102257 - 495 WP_219827445.1 CaiF/GrlA family transcriptional regulator -
HFS24_RS22940 (HFS24_22885) 102655..102795 - 141 WP_219827446.1 hypothetical protein -
HFS24_RS22945 (HFS24_22890) 103964..105091 - 1128 WP_219827447.1 TQO small subunit DoxD -
HFS24_RS22950 (HFS24_22895) 105719..105982 + 264 Protein_115 type II toxin-antitoxin system ParD family antitoxin -
HFS24_RS22955 (HFS24_22900) 105969..106265 + 297 WP_219827448.1 type II toxin-antitoxin system RelE/ParE family toxin -
HFS24_RS22960 (HFS24_22905) 106490..106756 + 267 WP_258169268.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
HFS24_RS22965 (HFS24_22910) 106743..107039 + 297 WP_219827449.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HFS24_RS22970 (HFS24_22915) 107404..108144 + 741 WP_219827450.1 tyrosine-type recombinase/integrase -
HFS24_RS22975 (HFS24_22920) 108470..109462 - 993 WP_219827536.1 RepB family plasmid replication initiator protein -
HFS24_RS22980 (HFS24_22925) 110317..110586 + 270 WP_001275014.1 DUF1778 domain-containing protein -
HFS24_RS22985 (HFS24_22930) 110590..111120 + 531 WP_219827451.1 GNAT family N-acetyltransferase -
HFS24_RS22990 (HFS24_22935) 111362..111970 + 609 WP_219827452.1 DUF2913 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..136285 136285


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Antitoxin ParD

(1-84)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11456.98 Da        Isoelectric Point: 5.8779

>T154028 WP_219827449.1 NZ_CP051369:106743-107039 [Salmonella enterica subsp. houtenae serovar 43:z4]
VKTVKLTPKASQDLEDIWYYGYHNFGEEQADKYVNQISGIFPVMSDHNIGTLRPELGEYICALPVERHMIYFLQTDTEIV
IIRILSHHQDAGRHLNWQ

Download         Length: 297 bp

>T154028 NZ_CP067303:c1821066-1820959 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9967.27 Da        Isoelectric Point: 4.9337

>AT154028 WP_258169268.1 NZ_CP051369:106490-106756 [Salmonella enterica subsp. houtenae serovar 43:z4]
MARTMTVDLGDELREFIESLIESGDYRTQSEVIRESLRLLREKQAESRLQTLRDLLAEGLSSGEPVAWEKDAFLKKVKAG
TRAAGENR

Download         Length: 267 bp

>AT154028 NZ_CP067303:1821113-1821179 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References