Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) parDE/-
Location 124580..124956 Replicon plasmid p30177-1
Accession NZ_CP051347
Organism Salmonella enterica subsp. enterica serovar Kentucky strain CVM 30177

Toxin (Protein)


Gene name parE Uniprot ID A0A075MDK3
Locus tag HFT18_RS23390 Protein ID WP_000969988.1
Coordinates 124580..124762 (-) Length 61 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag HFT18_RS23395 Protein ID WP_001324224.1
Coordinates 124759..124956 (-) Length 66 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HFT18_RS23380 122579..123613 - 1035 WP_001190234.1 3-deoxy-7-phosphoheptulonate synthase -
HFT18_RS23385 124173..124481 - 309 WP_000377483.1 hypothetical protein -
HFT18_RS23390 124580..124762 - 183 WP_000969988.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HFT18_RS23395 124759..124956 - 198 WP_001324224.1 toxin-antitoxin system protein Antitoxin
HFT18_RS23400 125638..126912 + 1275 WP_000489608.1 HlyD family secretion protein -
HFT18_RS23405 126887..129001 + 2115 WP_001183604.1 peptidase domain-containing ABC transporter -
HFT18_RS23410 129171..129482 - 312 WP_001259758.1 colicin V -
HFT18_RS23415 129460..129696 - 237 WP_001323890.1 colicin V immunity protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..146811 146811


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 61 a.a.        Molecular weight: 8995.79 Da        Isoelectric Point: 5.5500

>T153998 WP_000969988.1 NZ_CP051347:c124762-124580 [Salmonella enterica subsp. enterica serovar Kentucky]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Download         Length: 183 bp

>T153998 NZ_CP067299:543108-543395 [Escherichia coli]
ATGCCAATGGAGTTTGAATGGGATGAAAACAAGGCCAAAAGTAATCGGGTGAAACATGGCATCCGCTTTGAAGATGCGGT
GTTATTGTTTGATGATCCACAACATTTGTCACAGCAAGAACGCATAGAAAACGGTGAGTATCGCTGGCAGACAATCGGCC
TGGTTTACGGCATCGTGGTTATTCTGGTTGCGCATACCATCCGTTTCGAAAGCGGAAATGAAATTATTCGAATCATCAGT
GCACGAAAAGCAGATCGTAAAGAGAGGAATCGCTATGAGCATGGTTAA

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 9731.67 Da        Isoelectric Point: 5.5500

>AT153998 WP_001324224.1 NZ_CP051347:c124956-124759 [Salmonella enterica subsp. enterica serovar Kentucky]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Download         Length: 198 bp

>AT153998 NZ_CP067299:543382-543684 [Escherichia coli]
ATGAGCATGGTTAAACATAAACGAGGGACCTCCTCTACACTCGATGTGCAGCATGAGGCCGAACTGAAGGCGCTGGCGAA
TAAATCCGACGAAGATATTGATTACAGTGATATCCCACCTTCCAGCGATGAGCAATGGTCTAACGCCGAACGCGGTAAGT
TTTATCGGCCATTGAAAACTCAGGCTTCGGTGCGTATTGATGCTGATGTGATGGAATGGTTGAAGCGACCAGGTAAAGGC
TATCAAACTCGCCTGAACGCAATTTTACGTGAAGCGATGCTGCGCGATCAGAACAAAAAATAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A075MDK3


Antitoxin

Source ID Structure

References