Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | TsxAB/Xre(antitoxin) |
| Location | 7178..7679 | Replicon | plasmid p34514-1 |
| Accession | NZ_CP051327 | ||
| Organism | Salmonella enterica subsp. enterica serovar Senftenberg strain CVM 34514 | ||
Toxin (Protein)
| Gene name | TsxA | Uniprot ID | H1ZXU8 |
| Locus tag | HFT73_RS00100 | Protein ID | WP_000702247.1 |
| Coordinates | 7419..7679 (-) | Length | 87 a.a. |
Antitoxin (Protein)
| Gene name | TsxB | Uniprot ID | - |
| Locus tag | HFT73_RS00095 | Protein ID | WP_001132407.1 |
| Coordinates | 7178..7429 (-) | Length | 84 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HFT73_RS00055 | 2347..3048 | + | 702 | WP_000280995.1 | hypothetical protein | - |
| HFT73_RS00060 | 3095..3694 | + | 600 | WP_000091423.1 | hypothetical protein | - |
| HFT73_RS00065 | 3714..4040 | + | 327 | WP_000206701.1 | hypothetical protein | - |
| HFT73_RS00070 | 4171..4608 | - | 438 | WP_000466318.1 | type II toxin-antitoxin system HicB family antitoxin | - |
| HFT73_RS00075 | 4633..4815 | - | 183 | WP_000833470.1 | type II toxin-antitoxin system HicA family toxin | - |
| HFT73_RS00080 | 5373..5555 | + | 183 | WP_001481829.1 | hypothetical protein | - |
| HFT73_RS00085 | 5662..5928 | - | 267 | WP_000681608.1 | type II toxin-antitoxin system HicB family antitoxin | - |
| HFT73_RS00090 | 6348..6626 | - | 279 | WP_000545938.1 | hypothetical protein | - |
| HFT73_RS00095 | 7178..7429 | - | 252 | WP_001132407.1 | transcriptional regulator | Antitoxin |
| HFT73_RS00100 | 7419..7679 | - | 261 | WP_000702247.1 | hypothetical protein | Toxin |
| HFT73_RS00105 | 7731..7955 | - | 225 | WP_000814381.1 | hypothetical protein | - |
| HFT73_RS00110 | 8052..8261 | - | 210 | WP_000866036.1 | hypothetical protein | - |
| HFT73_RS00115 | 8303..8626 | - | 324 | WP_000427403.1 | hypothetical protein | - |
| HFT73_RS00120 | 9208..9537 | - | 330 | WP_000855120.1 | hypothetical protein | - |
| HFT73_RS00125 | 10135..10800 | + | 666 | WP_000532148.1 | P-loop NTPase | - |
| HFT73_RS00130 | 10874..11158 | + | 285 | WP_001162371.1 | hypothetical protein | - |
| HFT73_RS00135 | 11176..11772 | - | 597 | WP_000125165.1 | hypothetical protein | - |
| HFT73_RS00140 | 11922..12083 | - | 162 | WP_000775236.1 | type I toxin-antitoxin system Hok family toxin | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..58790 | 58790 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 87 a.a. Molecular weight: 12822.38 Da Isoelectric Point: 5.5500
>T153997 WP_000702247.1 NZ_CP051327:c7679-7419 [Salmonella enterica subsp. enterica serovar Senftenberg]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFF
Download Length: 261 bp
>T153997 NZ_CP067299:c506249-505992 [Escherichia coli]
ATGAATTTATCCCGTCAGGAACAACATACCTTACACGTTCTCGCTAAAGGTAGACGTATTGCGCACGTCCGCGATTCTTC
AGGCCGCGTCACTTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGTCCGTCAATGGCCAGCCCTATCGAATCAACACCACCGAGCTGAATAAAGTTCGCGCT
CAGCTCGATAATCGCTAA
ATGAATTTATCCCGTCAGGAACAACATACCTTACACGTTCTCGCTAAAGGTAGACGTATTGCGCACGTCCGCGATTCTTC
AGGCCGCGTCACTTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGTCCGTCAATGGCCAGCCCTATCGAATCAACACCACCGAGCTGAATAAAGTTCGCGCT
CAGCTCGATAATCGCTAA
Antitoxin
Download Length: 84 a.a. Molecular weight: 12380.85 Da Isoelectric Point: 5.5500
>AT153997 WP_001132407.1 NZ_CP051327:c7429-7178 [Salmonella enterica subsp. enterica serovar Senftenberg]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFF
Download Length: 252 bp
>AT153997 NZ_CP067299:c505980-505435 [Escherichia coli]
ATGACAGTACACCACTTCACTTTTCATATCACAGATAAAAGTGATGCCAGTGATATCCGGGAAGTCGAAACCCGCGCATT
TGGCTTCAGCAAAGAAGCCGATTTAGTGGCCTCTTTACTTGAGGATGAAAGCGCGCGCCCCGCGTTATCGCTGCTAGCCC
GGTATGAAGGCAAAGCCGTCGGGCATATTTTATTTACCCGGGCAACCTTCAAAGGAGAAATGGATTCACCGTTGATGCAC
ATCCTCGCTCCCCTGGCGGTCATACCGGAATACCAAGGGATGGGCGTGGGAGGACGGTTGATACGCACTGGCATCGAGCA
CCTGAGGTTGATGGGCTGCCAGACGGTTTTTGTTCTCGGCCACGCCACCTATTACCCCCGACATGGGTTCGAACCCTGTG
CCGGAGACAAAGGCTATCCGGCACCTTATCCCATCCCGGAGGAGCACAAAGCCTGCTGGATGATGCAATCACTCACCGCT
CAGCCCATGACCCTGACCGGCCACATCCGGTGCGCAGACCCTGATGAAACCGGAGCACTGACGTGA
ATGACAGTACACCACTTCACTTTTCATATCACAGATAAAAGTGATGCCAGTGATATCCGGGAAGTCGAAACCCGCGCATT
TGGCTTCAGCAAAGAAGCCGATTTAGTGGCCTCTTTACTTGAGGATGAAAGCGCGCGCCCCGCGTTATCGCTGCTAGCCC
GGTATGAAGGCAAAGCCGTCGGGCATATTTTATTTACCCGGGCAACCTTCAAAGGAGAAATGGATTCACCGTTGATGCAC
ATCCTCGCTCCCCTGGCGGTCATACCGGAATACCAAGGGATGGGCGTGGGAGGACGGTTGATACGCACTGGCATCGAGCA
CCTGAGGTTGATGGGCTGCCAGACGGTTTTTGTTCTCGGCCACGCCACCTATTACCCCCGACATGGGTTCGAACCCTGTG
CCGGAGACAAAGGCTATCCGGCACCTTATCCCATCCCGGAGGAGCACAAAGCCTGCTGGATGATGCAATCACTCACCGCT
CAGCCCATGACCCTGACCGGCCACATCCGGTGCGCAGACCCTGATGAAACCGGAGCACTGACGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|