Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | BrnTA/BrnT-BrnA |
| Location | 2579053..2579605 | Replicon | chromosome |
| Accession | NZ_CP051300 | ||
| Organism | Treponema sp. OMZ 305 | ||
Toxin (Protein)
| Gene name | brnT | Uniprot ID | - |
| Locus tag | ABK01_RS11465 | Protein ID | WP_253675730.1 |
| Coordinates | 2579303..2579605 (-) | Length | 101 a.a. |
Antitoxin (Protein)
| Gene name | brnA | Uniprot ID | - |
| Locus tag | ABK01_RS11460 | Protein ID | WP_212566621.1 |
| Coordinates | 2579053..2579322 (-) | Length | 90 a.a. |
Genomic Context
Location: 2579807..2580480 (674 bp)
Type: Others
Protein ID: Protein_2245
Type: Others
Protein ID: Protein_2245
Location: 2580473..2581894 (1422 bp)
Type: Others
Protein ID: WP_253675731.1
Type: Others
Protein ID: WP_253675731.1
Location: 2581908..2582543 (636 bp)
Type: Others
Protein ID: WP_253675732.1
Type: Others
Protein ID: WP_253675732.1
Location: 2574132..2574773 (642 bp)
Type: Others
Protein ID: WP_253675728.1
Type: Others
Protein ID: WP_253675728.1
Location: 2575181..2575975 (795 bp)
Type: Others
Protein ID: WP_016524140.1
Type: Others
Protein ID: WP_016524140.1
Location: 2575990..2576805 (816 bp)
Type: Others
Protein ID: WP_253675729.1
Type: Others
Protein ID: WP_253675729.1
Location: 2576896..2578605 (1710 bp)
Type: Others
Protein ID: WP_253676619.1
Type: Others
Protein ID: WP_253676619.1
Location: 2579053..2579322 (270 bp)
Type: Antitoxin
Protein ID: WP_212566621.1
Type: Antitoxin
Protein ID: WP_212566621.1
Location: 2579303..2579605 (303 bp)
Type: Toxin
Protein ID: WP_253675730.1
Type: Toxin
Protein ID: WP_253675730.1
Location: 2582584..2584434 (1851 bp)
Type: Others
Protein ID: WP_253675733.1
Type: Others
Protein ID: WP_253675733.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ABK01_RS11440 (ABK01_11555) | 2574132..2574773 | - | 642 | WP_253675728.1 | rod-binding protein | - |
| ABK01_RS11445 (ABK01_11560) | 2575181..2575975 | - | 795 | WP_016524140.1 | flagellar basal-body rod protein FlgG | - |
| ABK01_RS11450 (ABK01_11565) | 2575990..2576805 | - | 816 | WP_253675729.1 | flagellar basal-body rod protein FlgF | - |
| ABK01_RS11455 (ABK01_11570) | 2576896..2578605 | - | 1710 | WP_253676619.1 | DEAD/DEAH box helicase | - |
| ABK01_RS11460 (ABK01_11575) | 2579053..2579322 | - | 270 | WP_212566621.1 | BrnA antitoxin family protein | Antitoxin |
| ABK01_RS11465 (ABK01_11580) | 2579303..2579605 | - | 303 | WP_253675730.1 | BrnT family toxin | Toxin |
| ABK01_RS11470 (ABK01_11585) | 2579807..2580480 | + | 674 | Protein_2245 | DUF969 domain-containing protein | - |
| ABK01_RS11475 (ABK01_11590) | 2580473..2581894 | + | 1422 | WP_253675731.1 | DUF979 family protein | - |
| ABK01_RS11480 (ABK01_11600) | 2581908..2582543 | + | 636 | WP_253675732.1 | PrsW family glutamic-type intramembrane protease | - |
| ABK01_RS11485 (ABK01_11605) | 2582584..2584434 | - | 1851 | WP_253675733.1 | hypothetical protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 11616.13 Da Isoelectric Point: 5.6438
>T153971 WP_253675730.1 NZ_CP051300:c2579605-2579303 [Treponema sp. OMZ 305]
MDDGLFEWDNKKNTINRQKHGIGFEEALLVFDDPFHIELYDAAHSDKEDRFLAIGTVLNVLVVLVVYTERNQRIRIISAR
PATKKEKGLYYDAVNDTFRS
MDDGLFEWDNKKNTINRQKHGIGFEEALLVFDDPFHIELYDAAHSDKEDRFLAIGTVLNVLVVLVVYTERNQRIRIISAR
PATKKEKGLYYDAVNDTFRS
Download Length: 303 bp
>T153971 NZ_CP067261:4182765-4182983 [Klebsiella variicola]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAACTGGCGGTATTTTACTCAGCCGCCGATCATCGTCTGGCTGAAC
TGACCATGAATAAGCTGTACGATAAGATCCCGACCTCAGTCTGGAAGTTTATCCGCTAA
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAACTGGCGGTATTTTACTCAGCCGCCGATCATCGTCTGGCTGAAC
TGACCATGAATAAGCTGTACGATAAGATCCCGACCTCAGTCTGGAAGTTTATCCGCTAA
Antitoxin
Download Length: 90 a.a. Molecular weight: 10288.93 Da Isoelectric Point: 9.5104
>AT153971 WP_212566621.1 NZ_CP051300:c2579322-2579053 [Treponema sp. OMZ 305]
MTLSEAKSMLTQQRIEQLKTLAEQPIDTSDIPELTQEEFFKMYRPIKKPLSIRLDSDIIVWLKSYGKGYQSRINTILRNA
MAAEKQAAQ
MTLSEAKSMLTQQRIEQLKTLAEQPIDTSDIPELTQEEFFKMYRPIKKPLSIRLDSDIIVWLKSYGKGYQSRINTILRNA
MAAEKQAAQ
Download Length: 270 bp
>AT153971 NZ_CP067261:4182364-4182738 [Klebsiella variicola]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACTTCGGCTGTCAATCTTCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCGCTTAATTATAAAATTAAGTACACTGAGGATAATAAACTGGTCGCTCAGGTTGACGAATATCTG
GACGATACTTTTACCTTGTTCAGTAACTACGGCATTAACTCAACGGATTTGCAAAAGTGGAAAAAATCCGGTAATCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAATCCGGCCAGTCTCTCGTGTTAG
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACTTCGGCTGTCAATCTTCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCGCTTAATTATAAAATTAAGTACACTGAGGATAATAAACTGGTCGCTCAGGTTGACGAATATCTG
GACGATACTTTTACCTTGTTCAGTAACTACGGCATTAACTCAACGGATTTGCAAAAGTGGAAAAAATCCGGTAATCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAATCCGGCCAGTCTCTCGTGTTAG