Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 2856029..2856563 Replicon chromosome
Accession NZ_CP051293
Organism Mesorhizobium sp. NZP2077

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag HGP13_RS14070 Protein ID WP_172226186.1
Coordinates 2856264..2856563 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag HGP13_RS14065 Protein ID WP_172226183.1
Coordinates 2856029..2856274 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HGP13_RS14050 2851086..2853032 + 1947 WP_172226174.1 tetratricopeptide repeat protein -
HGP13_RS14055 2853130..2853519 + 390 WP_172226177.1 hypothetical protein -
HGP13_RS14060 2853923..2855959 + 2037 WP_172226180.1 tetratricopeptide repeat protein -
HGP13_RS14065 2856029..2856274 + 246 WP_172226183.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
HGP13_RS14070 2856264..2856563 + 300 WP_172226186.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HGP13_RS14075 2856621..2857349 - 729 WP_172234701.1 amino acid ABC transporter ATP-binding protein -
HGP13_RS14080 2857436..2858110 - 675 WP_019859628.1 amino acid ABC transporter permease -
HGP13_RS14085 2858107..2858778 - 672 WP_172226189.1 amino acid ABC transporter permease -
HGP13_RS14090 2858883..2859671 - 789 WP_172226192.1 ABC transporter substrate-binding protein -
HGP13_RS14095 2859776..2860936 - 1161 WP_172226195.1 saccharopine dehydrogenase family protein -
HGP13_RS14100 2860933..2861433 - 501 WP_027044322.1 Lrp/AsnC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-94)

Antitoxin

Antitoxin ParD

(3-81)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11851.54 Da        Isoelectric Point: 7.3994

>T153962 WP_172226186.1 NZ_CP051293:2856264-2856563 [Mesorhizobium sp. NZP2077]
MPGKSRQYRLSPLAEADLEDIWLYTFKQWSLEQADRYHRDLVDVIEALALGVKTGRRVDVREGYFKYPAGQHFIFFRQSE
TTLDVIRILHQRMDIERHL

Download         Length: 300 bp

>T153962 NZ_CP067256:53928-54410 [Klebsiella pneumoniae]
GTGGGACGTATAACCACGCCCGAGCCGTTATCCAGCTCTCATCAGCTGGCTGAGTTCGTCAGTGGAGAGACAGTCCTCGA
TGAATGGCTAAAACAGAGAGGTTTAAAAAATCAAGCTCTTGGCGCTGCCCGAACGTTCGTTGTTTGCAAGACGGGTACGA
AGCAAGTAGCTGGTTTTTACTCTTTGGCCACCGGTAGCGTTAACCATACGGAAGCGACAGGTAGTCTTCGGCGTAACATG
CCAGATCCTATACCGGTGATTATACTCGCTCGCCTGGCGGTAGATGTCTCATTGCACGGAAAAGGGGTTGGCGCCGATTT
ACTCCACGATGCAGTTCTACGGTGTTATCGCGTAGCTGAGAACATTGGGGTTCGTGCGATAATGGTTCATGCGCTTACTG
AAGAAGCCAAAGGTTTCTATGCTCACCATGGATTTAAGGCATCACAAACTCATGAGAGGACTCTGTTTCTAAAGCTTCCA
TGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8612.64 Da        Isoelectric Point: 7.3189

>AT153962 WP_172226183.1 NZ_CP051293:2856029-2856274 [Mesorhizobium sp. NZP2077]
VPRNTSVSLGDHFAGFIDTQVQTGRYGSASDVVRAGLRLLEEHEAKVAALQNALIAGEESGTPVAFDSASFLSRMKAKHA
R

Download         Length: 246 bp

>AT153962 NZ_CP067256:53674-53940 [Klebsiella pneumoniae]
ATGAAATCAGATGTTCAACTCAACCTAAGAGCTAAAGAGTCTCAGAGAGCACTCATCGATGCTGCTGCAGAGATCCTTCA
TAAATCGCGAACCGACTTTATCCTGGAGATGGCCTGCAAGGCTGCGGAGAATGTGATCCTTGATCGCCGTGTTTTCAATT
TTAACGACGAACAGTATGCAGAGTTCATCGATATGCTCGATGCACCAGTCGAGGATGAGCCCGCCATTAATAAACTACTG
GCAAGGAAACCTCAGTGGGACGTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References