153958

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 930028..930598 Replicon chromosome
Accession NZ_CP051291
Organism Helicobacter pylori strain ASHA-002

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HGI44_RS04505 Protein ID WP_202135255.1
Coordinates 930028..930300 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HGI44_RS04510 Protein ID WP_202135257.1
Coordinates 930287..930598 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HGI44_RS04485 926699..927466 - 768 WP_021301980.1 ABC transporter ATP-binding protein -
HGI44_RS04490 927466..928446 - 981 WP_202136083.1 iron ABC transporter permease -
HGI44_RS04495 928439..929281 - 843 WP_202136084.1 SDR family oxidoreductase -
HGI44_RS04500 929422..929946 + 525 WP_001120215.1 acyl-CoA thioesterase -
HGI44_RS04505 930028..930300 - 273 WP_202135255.1 type II toxin-antitoxin system YafQ family toxin Toxin
HGI44_RS04510 930287..930598 - 312 WP_202135257.1 hypothetical protein Antitoxin
HGI44_RS04515 930841..933087 - 2247 WP_202136085.1 outer membrane beta-barrel protein -
HGI44_RS04530 933405..934042 + 638 Protein_885 hypothetical protein -
HGI44_RS04535 933993..935105 - 1113 WP_202136086.1 hydrogenase formation protein HypD -
HGI44_RS04540 935124..935360 - 237 WP_078284132.1 HypC/HybG/HupF family hydrogenase formation chaperone -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10649.63 Da        Isoelectric Point: 9.7265

>T153958 WP_202135255.1 NZ_CP051291:c930300-930028 [Helicobacter pylori]
MLMIETSKKFDKDLKILVKNGFDLKFLYKVVENLAKEQPLDPKYKDHPLKGTLKDFRECHLKPDLLLVYQVKKQENTLFL
VRLGSHSELF

Download         Length: 273 bp

>T153958 NZ_CP067255:c4699150-4698809 [Klebsiella pneumoniae]
ATGAAAACTCTACCTGCAACAACTCCGCAGGCGGTGACGCTATGTCTGTCGTCTGTGGCAGTGTGGCAAATGCTGCTTGC
ACGCCTGCTGGAACAACATTATGGCCTGACACTCAACGACACACCATTCAGTGATGAAACGGTAATTCAGGAACATATCG
ATGCCGGTATATCTTTGGCCGATGCCGTTAATTTTCTGGTGGAAAAGTACGGGCTGGTTCGTATTGATCGCAAGGGATTC
AACTGGCAAGAACACTCCCCATATCTGCGGGCAGTTGATATTCTGCGGGCGCGACAGGCAACTGGTTTATTGCGCCGAAG
CCGTAAAAATGCTGTACGTTAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 12302.17 Da        Isoelectric Point: 10.3492

>AT153958 WP_202135257.1 NZ_CP051291:c930598-930287 [Helicobacter pylori]
MPNSPTKKDFTRYSEKQLFNFLNSIKTKQKRALEKLKEIQAQKQRIKKALQFKALHLTENGYTIEEEREILARAKDTKNH
LCFKSVEDFKKHCENLRFKNADD

Download         Length: 312 bp

>AT153958 NZ_CP067255:c4699512-4699171 [Klebsiella pneumoniae]
ATGAAATCTACTGACTCAGAGAACGATTCATTTCTCAAGTGGGGTCTGAATCGTAATGTGACACCTTGCTTTGGCGCTCG
TCTGGTACAGGAGGGAAACCGACTTCACTATCTGGCTGACCGGGCCAGCATTACCGGTGAATTCAGCAACGCAGAATCTT
TGAAGTTGGATGAGGTATTCCCACATTTTATCAGCCAGATGGAGTCGATGCTGACTACTGGTGAAATGAATCCTCGCCAT
GCCCACTTTTTCACCCTGTACCACAATGGTTTCACCTGCGAAGCCGATACCCTTGGCAGTTACGGCTACGTATACATCGC
CGTTTACCCCACTCAACGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References