Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 3820576..3821081 Replicon chromosome
Accession NZ_CP051261
Organism Xanthomonas sp. SI

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HEP75_RS15950 Protein ID WP_046978179.1
Coordinates 3820824..3821081 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A1C3TRJ9
Locus tag HEP75_RS15945 Protein ID WP_003468816.1
Coordinates 3820576..3820827 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HEP75_RS15915 3816430..3816726 - 297 WP_185824190.1 hypothetical protein -
HEP75_RS15920 3817514..3818119 - 606 WP_185826634.1 hypothetical protein -
HEP75_RS15925 3818142..3818333 - 192 WP_185824191.1 hypothetical protein -
HEP75_RS15930 3818372..3818815 - 444 WP_185824192.1 nuclear transport factor 2 family protein -
HEP75_RS15935 3818939..3819661 + 723 WP_185824193.1 ArsR family transcriptional regulator -
HEP75_RS15940 3819658..3820422 - 765 WP_185824194.1 endonuclease -
HEP75_RS15945 3820576..3820827 + 252 WP_003468816.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
HEP75_RS15950 3820824..3821081 + 258 WP_046978179.1 Txe/YoeB family addiction module toxin Toxin
HEP75_RS15960 3821367..3821720 - 354 WP_003468813.1 PilZ domain-containing protein -
HEP75_RS15965 3821717..3822694 - 978 WP_185824195.1 DNA polymerase III subunit delta' -
HEP75_RS15970 3822691..3823359 - 669 WP_185824196.1 dTMP kinase -
HEP75_RS15975 3823356..3824414 - 1059 WP_185824197.1 endolytic transglycosylase MltG -
HEP75_RS15980 3824490..3825839 - 1350 WP_185824198.1 aminodeoxychorismate synthase component I -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10173.68 Da        Isoelectric Point: 9.6587

>T153924 WP_046978179.1 NZ_CP051261:3820824-3821081 [Xanthomonas sp. SI]
VTLQFSDNAWEDYLYWQQTDKKMLKRVNDLIKAIQRDPFQGVGKPEPLRHALAGYWSRRINDEHRIVYKVEAGILLIAQV
RYHYV

Download         Length: 258 bp

>T153924 NZ_CP067246:107774-107923 [Escherichia coli]
ATGACGAAATATGCCCTTATCGGGTTGCTCGCCGTGTGTGCCACGGTATTGTGTTTTTCACTGATATTCAGGGAACGGTT
ATGTGAACTGAATATTCACAGGGGAAATACAGTGGTGCAGGTAACTCTGGCCTACGAAGCACGGAAGTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9281.56 Da        Isoelectric Point: 5.1186

>AT153924 WP_003468816.1 NZ_CP051261:3820576-3820827 [Xanthomonas sp. SI]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE

Download         Length: 252 bp

>AT153924 NZ_CP067246:c107729-107670 [Escherichia coli]
TAAGTACTTCATGCAGACCTCACGAGTTAATGGATTAACGAGTGGGGTCTTCGCATTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TRJ9

References