Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2181772..2182043 Replicon chromosome
Accession NZ_CP051219
Organism Escherichia coli strain SFE8

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2181902..2182005 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2181772..2182043 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HF527_RS10585 2178327..2178989 - 663 WP_000944256.1 exodeoxyribonuclease X -
HF527_RS10590 2179013..2179669 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
HF527_RS10595 2179771..2180001 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HF527_RS10600 2180140..2180514 + 375 WP_000204699.1 CopC domain-containing protein YobA -
HF527_RS10605 2180518..2181390 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
HF527_RS10610 2181403..2181744 + 342 WP_000976472.1 YebY family protein -
- 2181772..2182043 - 272 - - Antitoxin
- 2181902..2182005 + 104 - - Toxin
HF527_RS10615 2182140..2182796 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
HF527_RS10620 2182797..2182988 - 192 WP_001296140.1 YebW family protein -
HF527_RS10625 2183093..2183329 - 237 WP_001295499.1 DUF1480 family protein -
HF527_RS10630 2183447..2184886 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T153854 NZ_CP051219:2181902-2182005 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT153854 NZ_CP051219:c2182043-2181772 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ATGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References