Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 1009698..1010344 Replicon chromosome
Accession NZ_CP051217
Organism Sphingorhabdus sp. JK6

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag HF685_RS04855 Protein ID WP_168818534.1
Coordinates 1010054..1010344 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag HF685_RS04850 Protein ID WP_168818533.1
Coordinates 1009698..1010000 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HF685_RS04820 1005281..1005613 - 333 WP_168818527.1 DUF2834 domain-containing protein -
HF685_RS04825 1005626..1006135 - 510 WP_168818528.1 N-acetyltransferase -
HF685_RS04830 1006338..1006667 + 330 WP_168818529.1 hypothetical protein -
HF685_RS16075 1006704..1006898 - 195 WP_211051356.1 hypothetical protein -
HF685_RS04835 1007087..1008286 + 1200 WP_168818530.1 GGDEF domain-containing protein -
HF685_RS04840 1008431..1008955 - 525 WP_168818531.1 RidA family protein -
HF685_RS04845 1009042..1009554 - 513 WP_168818532.1 hypothetical protein -
HF685_RS04850 1009698..1010000 - 303 WP_168818533.1 putative addiction module antidote protein Antitoxin
HF685_RS04855 1010054..1010344 - 291 WP_168818534.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HF685_RS04860 1010739..1011002 + 264 WP_168818535.1 hypothetical protein -
HF685_RS04865 1011390..1011698 - 309 WP_168818536.1 hypothetical protein -
HF685_RS04870 1011797..1013707 - 1911 WP_168818537.1 phosphomethylpyrimidine synthase ThiC -
HF685_RS04875 1013966..1014370 - 405 WP_168818538.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-95)

Antitoxin

Uncharacterized protein HI1420

(3-98)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10873.58 Da        Isoelectric Point: 10.1284

>T153822 WP_168818534.1 NZ_CP051217:c1010344-1010054 [Sphingorhabdus sp. JK6]
MYRIEQTEEFADWLDGLRDRGAQAKIATRLVRVQSGLLGDWKSLGDGVSELRISYGPGYRLYYTMRGQTVIFLLCGSDKK
GQAKAIKRAKEMAKQI

Download         Length: 291 bp

>T153822 NZ_CP067141:236775-237101 [Paracoccus saliphilus]
GTGAAGCGCGGCGATCTTGTGACAGTCGCCCTTCAAGGTGACTATGGCAAGCCGCTCCCGGCGCTGATCATCCAGTCGGA
TCAATTTGATGAGCTCGGATCGGTGGTGATCCTGCCTCTTACCTCAACTCTGATTGATGCGCCGCTCCTCAGACCAACGG
TTGAGCCATCGTCCGATAACGGACTCCGCACGCCGTCACAGATCATGCTGGACAAGCCGATGACGGTGAAGACCGAAAAA
ATTGGACCCTCCTTCGGCCATCTCGATGATCTTGACATGATCGGCGTCAGCCGCTCCCTAGCGCTATTTCTCGGCTTGGC
AGGGTGA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10544.08 Da        Isoelectric Point: 5.1425

>AT153822 WP_168818533.1 NZ_CP051217:c1010000-1009698 [Sphingorhabdus sp. JK6]
MAKLKTKPFDAAKYITEPEHVVDLLNDALESGEAGYIANALGVVARSEGMTAIAEKSGVKRQALYRSLSEDGNPTLETLL
GVLGALDLRLTVKEGATKAA

Download         Length: 303 bp

>AT153822 NZ_CP067141:236560-236778 [Paracoccus saliphilus]
ATGCCAAGCCCTGTTTCTGAACGTGTCCAGAAGCGCCGGGACGCCCTGCGCGCTGCGGGCCTACGCCCTGTCCAAATCTG
GGTGCCCGATACGCGCCGCCCAGGCTTCGCTGCGGAGTGCCGGCGGCAGGCCGCGTTGATCGCCGCCTCAGATCGGGGCG
ACGCCGATCTGTCGGACTTCATGGATGCAGCCTTGAACGATCTGGATGAGTGGCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References