Detailed information of TA system TA153801

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 2726801..2727425
• Replicon: chromosome
• Accession: NZ_CP051208
• Organism: Acinetobacter sp. NEB149

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: N9R2M8
• Locus tag: HGD77_RS13115
• Protein ID: WP_004732265.1
• Coordinates: 2726801..2727187 (-)
• Length: 129 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: HGD77_RS13120
• Protein ID: WP_171054338.1
• Coordinates: 2727180..2727425 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HGD77_RS13100	2722105..2724387	-	2283	WP_168387020.1	TRAP transporter large permease subunit	-
HGD77_RS13105	2724585..2725157	-	573	WP_004732261.1	rhombosortase	-
HGD77_RS13110	2725225..2726265	-	1041	WP_004732263.1	hypothetical protein	-
HGD77_RS13115	2726801..2727187	-	387	WP_004732265.1	hypothetical protein	Toxin
HGD77_RS13120	2727180..2727425	-	246	WP_171054338.1	succinate dehydrogenase assembly factor 2	Antitoxin
HGD77_RS13125	2727622..2728794	+	1173	WP_004732268.1	acyl-CoA dehydrogenase family protein	-
HGD77_RS13130	2728855..2730345	-	1491	WP_004732270.1	NAD(P)/FAD-dependent oxidoreductase	-
HGD77_RS13135	2730563..2730928	-	366	WP_004281488.1	50S ribosomal protein L17	-
HGD77_RS13140	2730947..2731954	-	1008	WP_004281489.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (6-76)

Sequences

Toxin

Protein

• Length: 129 a.a.
• Molecular weight: 15229.34 Da
• Isoelectric Point: 9.9707

>T153801 WP_004732265.1 NZ_CP051208:c2727187-2726801 [Acinetobacter sp. NEB149]
MDNRCFKLKRSLCALAFQLFIFALLMYLLYQLLPIALWAVCAVIGLVIYQLFYRKTPQIEQFEYLDGREWSLTAKARSTR
RVCISHVIDHQAYIVVYFQHAKARPLLIWCDQLPFKQWKSLKLLTKLI

Nucleotide

• Length: 387 bp

>T153801 NZ_CP067101:c3092361-3092011 [Bradyrhizobium diazoefficiens]
ATGCCAAAGGTAGTAAAAACGACGGCCAAAACGGCATCCAAGACGACACGTTTCGACGCCGCCGACTATCTCGACACTGA
AGAGCGCCAGGCGGCCTATATCGCGGCCGCGCTGGAAACCGGCGACGCCGATTTCGTGCGCGACGCGCTCGGCCTCGTCG
CGCGAGCGCGCGGCATGAGCACGATAGCAAAGAAGGCCGGCTTAAACCGCGAAAGTTTGTACAAGGCGCTCGGAGAGACC
GGAAATCCCGAGTTCGGGACGGTCATGCGCATTGTCGGGGCGTTGGGCCTGACACTATCAGCCCAACCCGCGACAAGCGG
ACGAATGTCAAAGCGCCATCGCGCCGCCTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9878.34 Da
• Isoelectric Point: 4.9108

>AT153801 WP_171054338.1 NZ_CP051208:c2727425-2727180 [Acinetobacter sp. NEB149]
ISLEERKVIYRARRGLKELDVYFDPYVKNHYLNAEPFEKQMFAELVEQEDPDLLDWFMEVSEPPRPELKDFIKKLKFYVH
G

Nucleotide

• Length: 246 bp

>AT153801 NZ_CP067101:c3092642-3092361 [Bradyrhizobium diazoefficiens]
GTGCGGCAGACCAGACATTTTTCGGAGTGGCTGGACCGCCTCAAGGACGCCAATGCGGTCGCCCGGATCACGGCTCGCAT
TCGCCGCATGGAGTTGGACAATCCCGACGACAGCAAGAACGTGGGCCGCAACGTCCGAGAAATGCGCATCGACTACGGCG
CGGGCTACCGGATCTATTATGTGCAGCACGGAACGCAGATCATGATTCTGCTATGTGGCGGCGACAAGCGGACGCAACGA
CAAGACATCAAGCTAGCCCAGCAACTAGCGGAGACATTGTGA

Structures

Toxin

• AlphaFold DB: N9R2M8