Detailed information of TA system TA153799

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-MazE
• Location: 3533053..3533682
• Replicon: chromosome
• Accession: NZ_CP051206
• Organism: Dolichospermum flos-aquae CCAP 1403/13F

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: HGD76_RS17010
• Protein ID: WP_168696492.1
• Coordinates: 3533281..3533682 (+)
• Length: 134 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: HGD76_RS17005
• Protein ID: WP_168696491.1
• Coordinates: 3533053..3533280 (+)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HGD76_RS16985	3529203..3531335	+	2133	WP_168696489.1	GNAT family N-acetyltransferase	-
HGD76_RS16990	3531395..3531835	+	441	WP_168696490.1	ASCH domain-containing protein	-
HGD76_RS16995	3532276..3532518	+	243	WP_168507117.1	hypothetical protein	-
HGD76_RS17000	3532728..3533030	+	303	WP_168697476.1	type II toxin-antitoxin system VapC family toxin	-
HGD76_RS17005	3533053..3533280	+	228	WP_168696491.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
HGD76_RS17010	3533281..3533682	+	402	WP_168696492.1	type II toxin-antitoxin system VapC family toxin	Toxin
HGD76_RS17015	3533938..3534411	+	474	WP_148759972.1	type II toxin-antitoxin system VapC family toxin	-
HGD76_RS17020	3534415..3534582	+	168	WP_168466228.1	hypothetical protein	-
HGD76_RS17025	3534828..3535049	+	222	WP_148759970.1	type II toxin-antitoxin system HicB family antitoxin	-
HGD76_RS17030	3535269..3535670	-	402	WP_148759968.1	transcriptional regulator	-
HGD76_RS17035	3535793..3536080	-	288	WP_096668045.1	type II toxin-antitoxin system HigB family toxin	-
HGD76_RS17040	3536707..3537096	+	390	Protein_3330	response regulator transcription factor	-
HGD76_RS17045	3537334..3537516	-	183	WP_168696493.1	hypothetical protein	-
HGD76_RS17050	3537653..3537931	+	279	Protein_3332	DUF2854 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (3-123)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 134 a.a.
• Molecular weight: 15161.65 Da
• Isoelectric Point: 4.5216

>T153799 WP_168696492.1 NZ_CP051206:3533281-3533682 [Dolichospermum flos-aquae CCAP 1403/13F]
MQYLLDTNICIYLIKQKPEKVIARFQTLSISDIGISSITVAELEYGVYKSQQQEKNKNALMQFLLPLEIIEFSQDAAVIY
GYMRSDLESKGLVIGPMDMLIAAHSMSLDITLVTNNIREFSRIPNLLLENWAE

Nucleotide

• Length: 402 bp

>T153799 NZ_CP067101:c1411007-1410819 [Bradyrhizobium diazoefficiens]
ATGAATAGCCGGGAGATCATCGCGGCGCTGCAAGGGGATGGCTGGGTTCAAGTGGCTCAAAAGGGCAGCCACGTTCAGTT
CAAGCACCCGACCAAAAAGGGCCGCGTCACGGTCCCTCATCCGAAGCGGGACGTTCCGCTTGGGACCCTGAAGAGTATTG
AACGGCAGTCCGGCCTGAAGCTGAGGTGA

Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 8603.84 Da
• Isoelectric Point: 4.6325

>AT153799 WP_168696491.1 NZ_CP051206:3533053-3533280 [Dolichospermum flos-aquae CCAP 1403/13F]
MNTAKLSSDGTHQTVILPPDFKMTGTEVYIKKIGNAIILISKDNPWQTLIDSLNQFSDDFMMTRDQLPIDKREEF

Nucleotide

• Length: 228 bp

>AT153799 NZ_CP067101:c1410813-1410415 [Bradyrhizobium diazoefficiens]
ATGCGTCATTACATCGGTCTGATCCATAAGGATGCCAACAGCGATTTCGGCGTGTTGTTTCCCGATCTGCCGGGCCTTGT
GACCGCGGGGACCACGCTCGACGAAGCGCGCGACATGGCCGAGGAGGCGCTGGCGTTTCATCTCGAAGGTATGGCGGAAG
ACGGAGAGGCCATCCCGGAGCCTTCATCTCTCGAAGAGATCATGTCGAATCCCGAGAACCGTTCAGGCGTTGCCATTCTG
GTGTCGGTGAAGGACCACCAGCCAAAGATCGTACGCGTCAACGTCACCCTGCCCGGCGATGTGCTGGAGCAGATCGACAG
ATATGCCGAGGCCCACGGCTACACGCGTTCGGGCCTGCTTGCGCAGGCCGCGAAGAAGCTGATGACCGAAGCTGCCTGA