Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 1752178..1752755 Replicon chromosome
Accession NZ_CP051206
Organism Dolichospermum flos-aquae CCAP 1403/13F

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag HGD76_RS08560 Protein ID WP_168695524.1
Coordinates 1752411..1752755 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag HGD76_RS08555 Protein ID WP_168695523.1
Coordinates 1752178..1752417 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HGD76_RS08535 1747955..1749118 + 1164 WP_168695519.1 acyltransferase -
HGD76_RS08540 1749129..1750091 + 963 WP_168695520.1 glycosyltransferase -
HGD76_RS08545 1750155..1751129 + 975 WP_168695521.1 glycosyl transferase -
HGD76_RS08550 1751165..1752124 + 960 WP_168695522.1 glycosyltransferase -
HGD76_RS08555 1752178..1752417 + 240 WP_168695523.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
HGD76_RS08560 1752411..1752755 + 345 WP_168695524.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
HGD76_RS08565 1753070..1754299 + 1230 WP_168695525.1 glycosyltransferase -
HGD76_RS08570 1754435..1755337 + 903 WP_168695526.1 DUF2887 domain-containing protein -
HGD76_RS08575 1755707..1756492 + 786 WP_168695527.1 Uma2 family endonuclease -
HGD76_RS08580 1756780..1757706 + 927 WP_168695528.1 DUF4351 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1734757..1755337 20580


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(9-106)

Antitoxin

Antitoxin PemI-like

(1-79)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13116.14 Da        Isoelectric Point: 6.6926

>T153796 WP_168695524.1 NZ_CP051206:1752411-1752755 [Dolichospermum flos-aquae CCAP 1403/13F]
MVDYIPCHGDFIWLNFDPQSGHEQMGKRPALVLSQTEFNNYRGFIFVCPISTTKRKNPFYVEIPDGQAVKGIIMCDQLRS
LDFRSRIAEFISTCPENLLAEVLGHIYPILYKSN

Download         Length: 345 bp

>T153796 NZ_CP067098:4098878-4099186 [Pseudomonas sp. SW-3]
ATGAGCCAGACTTTGACTACTTTCGATATGGCGGCACTGCTGGACAGTGACGAAGCCATTAGCGAGTACCTCTCACAAGT
GCTCGCAGAGGGCGATAACGAGGAATTTCTTCGTGCTATCGGATACGTGGTGAAAGCGCGCGGAATGACACAGATTGCCA
AGGACTCGGGTATGGGTCGCGAAAGCCTGTACAAGGCCTTCGCGCCCGGTGCAAAACCACGCTTTGATACGGTTTTGAAG
GTCATCCATGCCCTCGGCATCGATCTCTGCGCGCAGCCAGGTCATTCGATCAATCACTCGGTGCTTTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9146.51 Da        Isoelectric Point: 4.5843

>AT153796 WP_168695523.1 NZ_CP051206:1752178-1752417 [Dolichospermum flos-aquae CCAP 1403/13F]
MKSQIGRWGNSLALRIPKYIADELALSINDEVDCRIEKGQLIVRLVQKFPKYTLSQLLSQELEPESEIDWGKPMGNEEW

Download         Length: 240 bp

>AT153796 NZ_CP067098:4098582-4098875 [Pseudomonas sp. SW-3]
ATGAATTATATTGTTCAACAAACTATGATCTTCGTGGCATGGCATGCCTCAGTTCGTGACTTGCGGGCGAAGATTGCTAT
CGCTCGTCGCATTGATCGTGCCTCTGCAGGTAACCTGGGTGATATCAAGCCGGTGGGAGACGGCGTTTCCGAAATGCGCG
TGGACGTCGGCGCCGGCTATCGGGTCTACTTCACTTTGCGAAACAGTGTCGTCATTGTGCTTTTGGCCGGTGGTGATAAA
TCTTCGCAAACCGCCGATATCAGGCGGGCTAAAAAATTGGCAAAGGAGGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References