Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 360609..361116 Replicon chromosome
Accession NZ_CP051206
Organism Dolichospermum flos-aquae CCAP 1403/13F

Toxin (Protein)


Gene name relB Uniprot ID A0A6H2BW57
Locus tag HGD76_RS01880 Protein ID WP_027401524.1
Coordinates 360856..361116 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A6H2BVA9
Locus tag HGD76_RS01875 Protein ID WP_027401523.1
Coordinates 360609..360863 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HGD76_RS01850 355979..357325 + 1347 WP_148762601.1 N-acetylmuramoyl-L-alanine amidase -
HGD76_RS01855 357453..358112 + 660 WP_168694792.1 rhomboid family intramembrane serine protease -
HGD76_RS01860 358343..358819 - 477 WP_168694793.1 DUF1499 domain-containing protein -
HGD76_RS01865 359559..359957 - 399 WP_168694794.1 hypothetical protein -
HGD76_RS01870 359954..360253 - 300 WP_168694795.1 hypothetical protein -
HGD76_RS01875 360609..360863 + 255 WP_027401523.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
HGD76_RS01880 360856..361116 + 261 WP_027401524.1 Txe/YoeB family addiction module toxin Toxin
HGD76_RS01885 361765..363030 - 1266 WP_168697334.1 glycosyltransferase family 4 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10336.87 Da        Isoelectric Point: 7.9759

>T153790 WP_027401524.1 NZ_CP051206:360856-361116 [Dolichospermum flos-aquae CCAP 1403/13F]
MSRMLAWTDEAWGNYLYWQGQDKKTLKRINKLIEETMRMPFEGIGKPEPLKENLAGFWSRRIDDTNRLVYAVDDVYVTII
SCRYHY

Download         Length: 261 bp

>T153790 NZ_CP067094:261925-262209 [Klebsiella michiganensis]
ATGACCTATAAGTTAGCCTTCAATGAATCAGCTTTGAAAGAATGGAAAAAACTGGGTCATACTATTCGGGAGCAATTCAA
AAAGAAGCTTTCCGAACGGCTTCAGAACCCACGGGTGCCCGCAGCACAACTCCATGGAGGTAAAGACCAGTATAAAATAA
AGCTCCATGGCGCGGGTTACCGACTGGTTTACAGTGTCAACGATGAAATTGTGACGGTCACCGTAATTGGGGTGGGCAAA
CGCAACAATGATGATATCTACAACGCAACCCGACACAGAAATTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9554.87 Da        Isoelectric Point: 5.0623

>AT153790 WP_027401523.1 NZ_CP051206:360609-360863 [Dolichospermum flos-aquae CCAP 1403/13F]
MKIISFSEARNSLKTVLDQVTEDADYTIITRRDADDTVVMSLEFFNSLMETVHLLKSPANAAHLERSIAQFKQGKVVQRD
LLNE

Download         Length: 255 bp

>AT153790 NZ_CP067094:261687-261935 [Klebsiella michiganensis]
ATGGCATTTCAGGTTTTAACCACCACAGCAGCCAGCATTACAGAACTTAAACGTGACCCTATGGGTACCTTCAATGCAGG
AGAAGGTGCACCGGTAGCAATCCTGAATCGCAACGAACCCGCTTTTTACTGTGTACCACCAGCCCTGTATGCTCAGCTGA
TGGAAATGCTGGAAGATCAAGAGTTGGGGCGTATTGCTGATGAACGAATCGGTGAGGACCGAATCGAGGTCAACATTGAT
GACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6H2BW57

Antitoxin

Source ID Structure
AlphaFold DB A0A6H2BVA9

References