Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 2438293..2438800 Replicon chromosome
Accession NZ_CP051197
Organism Treponema vincentii strain OMZ 802

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag E4N70_RS11050 Protein ID WP_253818241.1
Coordinates 2438510..2438800 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag E4N70_RS11045 Protein ID WP_253818240.1
Coordinates 2438293..2438520 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E4N70_RS11035 (E4N70_10975) 2434219..2436183 - 1965 WP_253818238.1 fructose-1,6-bisphosphatase -
E4N70_RS11040 (E4N70_10980) 2436372..2438027 + 1656 WP_253818239.1 ATP-binding cassette domain-containing protein -
E4N70_RS11045 (E4N70_10985) 2438293..2438520 + 228 WP_253818240.1 hypothetical protein Antitoxin
E4N70_RS11050 (E4N70_10990) 2438510..2438800 + 291 WP_253818241.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
E4N70_RS11060 (E4N70_11000) 2439397..2439801 + 405 WP_253818242.1 thioesterase family protein -
E4N70_RS11065 (E4N70_11005) 2440269..2442362 + 2094 WP_253818244.1 methyl-accepting chemotaxis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11330.23 Da        Isoelectric Point: 10.0676

>T153771 WP_253818241.1 NZ_CP051197:2438510-2438800 [Treponema vincentii]
MAYKIEFEAQALAEFSNLDGAVKKQIRKYIDKLAEREDPRTLGEPLQSNLSMFWKYRVGDYRLVAEIQDEKLVVLMLVIA
HRRVVYKTADKRLNRK

Download         Length: 291 bp

>T153771 NZ_CP067091:c1968077-1967974 [Salmonella enterica subsp. enterica serovar Typhimurium]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8615.83 Da        Isoelectric Point: 6.3204

>AT153771 WP_253818240.1 NZ_CP051197:2438293-2438520 [Treponema vincentii]
MTQAIVTRFDIDTVNRLIRLAEMTGRPKSYYIKEAVNEKLDELELAYLAQSRAEDVRAGRSITVSWEDVKKQNGL

Download         Length: 228 bp

>AT153771 NZ_CP067091:1967972-1968117 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References